4-2-吡啶-2-甲基-3-丁基-2-醇合成路线 （共 8 条）
反应条件
copper(l) iodide; triethylamine; triphenylphosphine T=90°C; Sonogashira coupling; 3 h; Inert atmosphere;
参考文献
Molecules, , vol. 15, # 12 p. 9157 - 9173
反应条件
copper(l) iodide; diisopropylamine; triphenylphosphine; palladium on activated charcoal in N,N-dimethyl acetamide; water T=80°C; Sonogashira coupling; 24 h;
参考文献
Journal of Organic Chemistry, , vol. 68, # 8 p. 3327 - 3329
反应条件
1: pyridin-2-ylacetylene With n-butyllithium in tetrahydrofuran; hexane T=-42°C; 1.5 h; 2: acetone in tetrahydrofuran; hexane T=-78 - 20°C; 7 h; Further stages.;
参考文献
Organic Letters, , vol. 9, # 22 p. 4547 - 4550
反应条件
tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran T=50 - 55°C; 8 h;
参考文献
Heterocycles, , vol. 46, # 1 p. 209 - 214
反应条件
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine; triphenylphosphine Inert atmosphereSealed flaskHeating;
参考文献
Tetrahedron, , vol. 68, # 13 p. 2844 - 2850
反应条件
sodium hydroxide; copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); N-benzyl-N,N,N-triethylammonium chloride in benzene Ambient temperature; Yield given;
参考文献
Synthesis, , # 7 p. 571 - 572
反应条件
sodium hydroxide in toluene Heating;
参考文献
Ames, D. E.; Bull, D.; Takundwa, C.
Synthesis, 1981 , # 5 p. 364 - 365
反应条件
copper(l) iodide; palladium 10 on activated carbon; triethylamine; triphenylphosphine; sodium hydroxide in acetonitrile
T=75°C; Sonogashira coupling; 24 h; Inert atmosphere;
参考文献
Adriaenssens, Louis; Severa, Lukas; Salova, Tereza; Cisarova, Ivana; Pohl, Radek; Saman, David; Rocha, Silvia V.; Finney, Nathaniel S.; Pospisil, Lubomir; Slavicek, Petr; Teply, Filip
Chemistry - A European Journal, 2009 , vol. 15, # 5 p. 1072 - 1076
