2-溴-5-羟基-4-甲氧基苯甲醛合成路线 （共 39 条）
反应条件
bromine; acetic acid
参考文献
Journal of the Chemical Society, , p. 6914 - 6922
反应条件
sulfuric acid T=90°C; 6 h; Inert atmosphereLarge scale; regioselective reaction;
参考文献
Kueenburg, Bernhard; Czollner, Laszlo; Frohlich, Johannes; Jordis, Ulrich
Organic Process Research and Development, 1999 , vol. 3, # 6 p. 425 - 431
反应条件
potassium tert-butylate in methanol; dimethyl sulfoxide T=50°C; 0.5 h;
参考文献
Imakura; Okimoto; Konishi; Hisazumi; Yamazaki; Kobayashi; Yamashita
Chemical and Pharmaceutical Bulletin, 1992 , vol. 40, # 7 p. 1691 - 1696
反应条件
hydrogenchloride in water T=90°C; 10 h;
参考文献
Chen, Han; Long, Haitao; Cui, Xiaojie; Zhou, Jiang; Xu, Ming; Yuan, Gu
Journal of the American Chemical Society, 2014 , vol. 136, # 6 p. 2583 - 2591
反应条件
hydrogen bromide; bromine in acetic acid
参考文献
Chaplin, David A.; Fraser, Neil; Tiffin, Peter D.
Tetrahedron Letters, 1997 , vol. 38, # 45 p. 7931 - 7932
反应条件
in methanol; dimethyl sulfoxide; N,N-dimethyl-formamide T=150°C; 3 h;
参考文献
Kobayashi, Shigeru; Okimoto, Kazuto; Imakura, Yasuhiro
Chemical & Pharmaceutical Bulletin, 1982 , vol. 30, # 5 p. 1567 - 1573
反应条件
sodium methylate in dimethyl sulfoxide T=150°C; 0.0194444 h;
参考文献
Chemical & Pharmaceutical Bulletin, , vol. 28, # 4 p. 1287 - 1293
反应条件
chloro-trimethyl-silane; sodium iodide in dichloromethane debenzylation;
参考文献
Ohmori, Osamu; Takayama, Hiromitsu; Kitajima, Mariko; Aimi, Norio
Chemical and Pharmaceutical Bulletin, 1999 , vol. 47, # 10 p. 1512 - 1513
反应条件
sodium methylate in N,N-dimethyl-formamide T=100 - 105°C; 1.5 h;
参考文献
Journal of Organic Chemistry USSR (English Translation), , vol. 27, # 7 p. 1380 - 1381
Zhurnal Organicheskoi Khimii, , vol. 27, # 7 p. 1578 - 1579
反应条件
methanol; sodium methylate; dimethyl sulfoxide T=170°C; 0.333333 h;
参考文献
Heterocycles, , vol. 31, # 6 p. 1067 - 1076
