2-溴-3-羟基-4-甲氧基苯甲醛合成路线 （共 32 条）
反应条件
bromine; sodium acetate; iron in acetic acid 5 h;
参考文献
Organic and Biomolecular Chemistry, , vol. 5, # 9 p. 1466 - 1471
反应条件
palladium diacetate; (iPr)NEt; triphenylphosphine in acetonitrile T=100°C;
参考文献
Journal of the American Chemical Society, , vol. 127, # 42 p. 14785 - 14803
反应条件
bromine in tetrachloromethane 2 h; Ambient temperature; Yield given;
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 21, # 2 p. 95 - 97
反应条件
1: trifluoroacetic acid / dichloromethane / 1 h / Inert atmosphere 2: water / acetonitrile / Inert atmosphere; Acidic conditions View Scheme
参考文献
Canadian Journal of Chemistry, , vol. 89, # 6 p. 709 - 728
反应条件
water; oxalic acid Inert atmosphere;
参考文献
Canadian Journal of Chemistry, , vol. 89, # 6 p. 709 - 728
反应条件
bromine; acetic acid
参考文献
Journal of the Chemical Society, , p. 2279,2287
Journal of Organic Chemistry, , vol. 5, p. 204,208
反应条件
1.1: tris-(dibenzylideneacetone)dipalladium(0); tri-tert-butyl phosphine; potassium carbonate / toluene / 16 h / 110 °C / Inert atmosphere 1.2: 16 h / 0 - 25 °C / Inert atmosphere 2.1: 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione / N,N-dimethyl-formamide / 16 h / 0 - 25 °C / Inert atmosphere 3.1: trifluoroacetic acid / dichloromethane / 1 h / Inert atmosphere 4.1: water / acetonitrile / Inert atmosphere; Acidic conditions View Scheme
参考文献
Canadian Journal of Chemistry, , vol. 89, # 6 p. 709 - 728
反应条件
1: 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione / N,N-dimethyl-formamide / 16 h / 0 - 25 °C / Inert atmosphere 2: trifluoroacetic acid / dichloromethane / 1 h / Inert atmosphere 3: water / acetonitrile / Inert atmosphere; Acidic conditions View Scheme
参考文献
Canadian Journal of Chemistry, , vol. 89, # 6 p. 709 - 728
反应条件
1.1: toluene-4-sulfonic acid / tetrahydrofuran / 2 h / Inert atmosphere; Reflux 2.1: tributylphosphine; di-isopropyl azodicarboxylate / tetrahydrofuran / 12 h / 4 - 25 °C / Inert atmosphere 3.1: tris-(dibenzylideneacetone)dipalladium(0); tri-tert-butyl phosphine; potassium carbonate / toluene / 16 h / 110 °C / Inert atmosphere 3.2: 16 h / 0 - 25 °C / Inert atmosphere 4.1: 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione / N,N-dimethyl-formamide / 16 h / 0 - 25 °C / Inert atmosphere 5.1: trifluoroacetic acid / dichloromethane / 1 h / Inert atmosphere 6.1: water / acetonitrile / Inert atmosphere; Acidic conditions View Scheme
参考文献
Canadian Journal of Chemistry, , vol. 89, # 6 p. 709 - 728
反应条件
1.1: tributylphosphine; di-isopropyl azodicarboxylate / tetrahydrofuran / 12 h / 4 - 25 °C / Inert atmosphere 2.1: tris-(dibenzylideneacetone)dipalladium(0); tri-tert-butyl phosphine; potassium carbonate / toluene / 16 h / 110 °C / Inert atmosphere 2.2: 16 h / 0 - 25 °C / Inert atmosphere 3.1: 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione / N,N-dimethyl-formamide / 16 h / 0 - 25 °C / Inert atmosphere 4.1: trifluoroacetic acid / dichloromethane / 1 h / Inert atmosphere 5.1: water / acetonitrile / Inert atmosphere; Acidic conditions View Scheme
参考文献
Canadian Journal of Chemistry, , vol. 89, # 6 p. 709 - 728
