2-[(4-氯苯基)甲基]丙二腈合成路线 （共 10 条）
反应条件
sodium tetrahydroborate in tetrahydrofuran; water 0.0833333 h; Ambient temperature;
参考文献
Mauger, J.; Robert, A.
Tetrahedron, 1988 , vol. 44, # 9 p. 2493 - 2502
反应条件
diethyl-1,4-dihydro-2,6-dimethyl-3,5-pyridine dicarboxylate T=20°C; 1.5 h;
参考文献
Zhang, Ze; Gao, Jie; Xia, Jing-Jing; Wang, Guan-Wu
Organic and Biomolecular Chemistry, 2005 , vol. 3, # 9 p. 1617 - 1619
反应条件
phenanthrene in acetonitrile 46 h; Irradiation300 W high pressure mercury lamp, λ>280 nm;
参考文献
Mizuno, Kazuhiko; Nakanishi, Kazuhisa; Chosa, Jun-ichi; Nguyen, Tien; Otsuji, Yoshio
Tetrahedron Letters, 1989 , vol. 30, # 28 p. 3689 - 3692
反应条件
1: malononitrile With sodium hydride in tetrahydrofuran; N,N-dimethyl-formamide T=20°C; 2 h; 2: p-ClC6H4CH2Hal in tetrahydrofuran; N,N-dimethyl-formamide T=20°C;
参考文献
Wu, Zhong-Liu; Li, Zu-Yi
Tetrahedron Asymmetry, 2003 , vol. 14, # 15 p. 2133 - 2142
反应条件
phosphorus pentoxide
参考文献
Russell; Hitchings
Journal of the American Chemical Society, 1952 , vol. 74, p. 3443
参考文献
Itoh, Kazuyoshi; Ishida, Hideaki; Chikashita, Hidenori
Chemistry Letters, 1982 , p. 1117 - 1118
反应条件
1: NH3; sodium methylate; methanol 2: P2O5 View Scheme
参考文献
Russell; Hitchings
Journal of the American Chemical Society, 1952 , vol. 74, p. 3443
反应条件
1.1: aluminum oxide / Inert atmosphere 2.1: benzaldehyde; 1,2-diamino-benzene / tetrahydrofuran / 24 h / 20 °C / Inert atmosphere 2.2: 0.17 h / Irradiation View Scheme
参考文献
Feng, Yi-Si; Yang, Chun-Yan; Huang, Qiang; Xu, Hua-Jian
Tetrahedron, 2012 , vol. 68, # 25 p. 5053 - 5059
反应条件
in acetonitrile T=20°C; Reduction; oxidation; 17 h; Kinetics; Further Variations:Temperatures;
参考文献
Zhu, Xiao-Qing; Zou, Hong-Ling; Yuan, Ping-Wei; Cao, Lei; Cheng, Jin-Pei
Journal of the Chemical Society. Perkin Transactions 2, 2000 , # 9 p. 1857 - 1861
反应条件
1: 2-(4'-chlorophenyl)-1,1-dicyanoethane With potassium hydride in acetonitrile
T=20°C; 0.333333 h; Inert atmosphereGlovebox;
2: 4-acetylamino-2,2,6,6-tetramethylpiperidine-1-oxoammonium in acetonitrile
T=24.84°C; Inert atmosphereGlovebox; Thermodynamic data;
参考文献
Cao, Ying; Zhang, Song-Chen; Zhang, Min; Shen, Guang-Bin; Zhu, Xiao-Qing
Journal of Organic Chemistry, 2013 , vol. 78, # 14 p. 7154 - 7168
