5-氯-2-甲氧基苯甲酰氯合成路线 (共 23 条)
反应条件
in thionyl chloride; benzene
参考文献
Chubb; Francis L.; Eric; Lucien
Patent: US3965173 A1, 1976 ;
反应条件
N,N-dimethyl-formamide in dichloromethane
参考文献
US2003/55085 A1, ;
US 20030055085 A1
反应条件
1: 10 percent sodium hydroxide / 16 h / Ambient temperature 2: thionyl chloride / 1.) room temperature, 0.5 h, 2.) reflux, 0.5 h View Scheme
参考文献
Journal of the American Chemical Society, , vol. 110, p. 7178
反应条件
potassium hydroxide; acetic acid in ethanol; water
参考文献
American Home Products Corporation
Patent: US4895860 A1, 1990 ;
反应条件
2-(N,N-dimethylamino)-pyridine in pyridine
参考文献
Hoechst Aktiengesellschaft
Patent: US5574069 A1, 1996 ;
反应条件
sodium hydroxide in acetone 2 h;
参考文献
Brown, George R.; Foubister, Alan J.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 1 p. 79 - 81
反应条件
bis[2-(N,N-dimethylamino)ethyl] ether in tetrahydrofuran Grignard reaction; cooling;
参考文献
Wang, Xiao-Jun; Zhang, Li; Sun, Xiufeng; Xu, Yibo; Krishnamurthy, Dhileepkumar; Senanayake, Chris H.
Organic Letters, 2005 , vol. 7, # 25 p. 5593 - 5595
反应条件
triethylamine in toluene Heating;
参考文献
Calderone, Vincenzo; Coi, Alessio; Fiamingo, Francesca Lidia; Giorgi, Irene; Leonardi, Michele; Livi, Oreste; Martelli, Alma; Martinotti, Enrica
European Journal of Medicinal Chemistry, 2006 , vol. 41, # 12 p. 1421 - 1429
参考文献
European Journal of Medicinal Chemistry, , vol. 39, # 10 p. 835 - 847
反应条件
sodium hydroxide in acetone
2 h;
参考文献
Brown, George R.; Foubister, Alan J.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 1 p. 79 - 81