1: 2-(pyrrolidin-1-ylmethyl)-1H-benzimidazole With sodium hydride in tetrahydrofuran; mineral oil T=0°C; 0.0833333 h; Inert atmosphere; 2: p-bromomethylchlorobenzene With tetrabutylammomium bromide in tetrahydrofuran; mineral oil T=20°C; Inert atmosphere;
参考文献
Vlahakis, Jason Z.; Vukomanovic, Dragic; Nakatsu, Kanji; Szarek, Walter A.
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 21 p. 6788 - 6795