2-氯烟酸合成路线

2942-59-82-氯烟酸→38029-99-12-氯-3-N,N-二乙基吡啶羧酰胺

参考文献

Dormoy, Jean-Robert; Heymes, Alain
Tetrahedron, 1993 , vol. 49, # 14 p. 2885 - 2914

参考文献

Kretzschmar
Die Pharmazie, 1980 , vol. 34, # 5-6 p. 253 - 256

2942-59-82-氯烟酸+74497-02-2→56149-29-22-氯-N-苯基烟酰胺

参考文献

BIOTA SCIENTIFIC MANAGEMENT PTY LTD; DRAFFAN, Alistair George; HUFTON, Richard; POOL, Brett Raymond; HARDING, Michael; JAHANGIRI, Saba; JEYNES, Tyrone Pieter; CIANCI, Julia; FREY, Barbara
Patent: WO2011/153588 A1, 2011 ;
Location in patent: Page/Page column 40 ;
WO 2011/153588 A1

2942-59-82-氯烟酸→56149-29-22-氯-N-苯基烟酰胺

参考文献

Parashiva Prabhu; Phadnis, Prasad P.; Wadawale, Amey P.; Indira Priyadarsini; Jain, Vimal K.
Journal of Organometallic Chemistry, 2012 , vol. 713, p. 42 - 50

2942-59-82-氯烟酸→56149-32-7N-丁基-2-氯烟酰胺

参考文献

Zhang, Zhichao; Liu, Chengwu; Li, Xiangqian; Song, Ting; Wu, Zhiyong; Liang, Xiaomeng; Zhao, Yan; Shen, Xiaoyun; Chen, Hongbo
European Journal of Medicinal Chemistry, 2013 , vol. 60, p. 410 - 420

2942-59-82-氯烟酸+106-41-24-溴苯酚→61532-37-4

参考文献

INTERMUNE, INC.; BUCKMAN, Brad, O.; NICHOLAS, John, B.; EMAYAN, Kumaraswamy; SEIWERT, Scott, D.
Patent: WO2013/25733 A1, 2013 ;
Location in patent: Paragraph 0421 ;

2942-59-82-氯烟酸+1461624-35-0+61532-37-4→61532-38-5

参考文献

Schrimpf, Michael R.; Sippy, Kevin B.; Ji, Jianguo; Li, Tao; Frost, Jennifer M.; Briggs, Clark A.; Bunnelle, William H.
Patent: US2005/234031 A1, 2005 ;
Location in patent: Page/Page column 66 ;

3731-53-14-甲氨基吡啶+2942-59-82-氯烟酸→854382-06-22-[(4-吡啶甲基)氨基]烟酸

参考文献

Dominguez, Celia; Smith, Leon; Huang, Qi; Yuan, Chester; Ouyang, Xiaohu; Cai, Lynn; Chen, Paul; Kim, Joseph; Harvey, Timothy; Syed, Rashid; Kim, Tae-Seong; Tasker, Andrew; Wang, Ling; Zhang, Michael; Coxon, Angela; Bready, James; Starnes, Charles; Chen, Danlin; Gan, Yongmei; Neervannan, Sesha; Kumar, Gondi; Polverino, Anthony; Kendall, Richard
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 21 p. 6003 - 6008