2-氨基-5-甲基苯甲酸合成路线 （共 102 条）
反应条件
hydrogen; palladium 10 on activated carbon in ethanol T=20°C;
参考文献
AVANIR PHARMACEUTICALS
Patent: WO2004/74218 A2, 2004 ;
Location in patent: Page 97 ;
反应条件
1: With sodium N-bromobenzenesulfonamide; sodium hydroxide; palladium dichloride in water; acetonitrile T=60°C; pH=12; 3.33333 h; 2: in water Acidic conditions;
参考文献
Karthikeyan; Jagadeesh, Rajenahally V.; Sree Sandhya; Puttaswamy; Nithya; Kumar, S. Senthil; Bhagat
Applied Organometallic Chemistry, 2011 , vol. 25, # 1 p. 34 - 46
反应条件
1: With sodium N-bromobenzenesulfonamide; sodium hydroxide; palladium dichloride in water; acetonitrile T=60°C; pH=12; 2 h; 2: in water Acidic conditions;
参考文献
Kumar, C. Vinod; Shivananda; Raju, C. Nagu; Jagadeesh
Synthetic Communications, 2010 , vol. 40, # 23 p. 3480 - 3487
反应条件
sodium hydroxide; dihydrogen peroxide T=10 - 15°C;
参考文献
Knorr,R. et al.
Chemische Berichte, 1979 , vol. 112, p. 3490 - 3514
反应条件
1: fuming nitric acid 2: tin; hydrochloric acid View Scheme
参考文献
Findeklee
Chemische Berichte, 1905 , vol. 38, p. 3555
反应条件
hydrogenchloride T=100°C;
参考文献
Ehrlich
Chemische Berichte, 1901 , vol. 34, p. 3366
反应条件
1: durch Nitrieren 2: fuming hydrochloric acid / 150 °C / im geschlossenen Rohr 3: tin; hydrochloric acid View Scheme
参考文献
Findeklee
Chemische Berichte, 1905 , vol. 38, p. 3555
参考文献
Kisber; Glagolewa
Zhurnal Obshchei Khimii, 1953 , vol. 23, p. 1028,1030; engl. Ausg. S. 1077, 1079
Full Text Show Details
Dokunichin; Gaewa
Zhurnal Obshchei Khimii, 1953 , vol. 23, p. 606,609; engl. Ausg. S. 629, 632
反应条件
1: AlCl3; NaCl / 140 °C 2: aqueous KOH View Scheme
参考文献
Dokunichin; Gaewa
Zhurnal Obshchei Khimii, 1953 , vol. 23, p. 606,609; engl. Ausg. S. 629, 632
反应条件
1: concentrated sulfuric acid; potassium nitrate 2: tin; fuming hydrochloric acid 3: fuming hydrochloric acid / 100 °C View Scheme
参考文献
Ehrlich
Chemische Berichte, 1901 , vol. 34, p. 3366
