1,5,9-三氮杂环十二烷合成路线 （共 19 条）
反应条件
sulfuric acid T=100 - 105°C; Heating50-70 h;
参考文献
Luk'yanenko, N.G.; Basok, S.S.; Filonova, L.K.
Journal of Organic Chemistry USSR (English Translation), 1988 , vol. 24, p. 1562 - 1571
Zhurnal Organicheskoi Khimii, 1988 , vol. 24, # 8 p. 1731 - 1742
反应条件
sulfuric acid 9.5 h; Heating;
参考文献
Kim; Wilson; Haseltine
Synthetic Communications, 1994 , vol. 24, # 21 p. 3109 - 3114
反应条件
cesium fluoride in N,N-dimethyl-formamide T=95°C; 24 h;
参考文献
Hoye; Richman; Dantas; Lightbourne; Scott Shinneman
Journal of Organic Chemistry, 2001 , vol. 66, # 8 p. 2722 - 2725
反应条件
1: 70 percent / sodium hydroxide / H2O / 1.) 1 hr., 5 deg C, 2.) r.t., 3 hrs. 2: 90 percent / tetrabutylammonium iodide, sodium hydroxide (50 percent) / toluene; H2O / 9 h / Heating 3: 63 percent / sulfuric acid, (conc.) / 39 h / 100 °C View Scheme
参考文献
Journal of Organic Chemistry USSR (English Translation), , vol. 24, p. 1562 - 1571
Zhurnal Organicheskoi Khimii, , vol. 24, # 8 p. 1731 - 1742
反应条件
1: 90 percent / tetrabutylammonium iodide, sodium hydroxide (50 percent) / toluene; H2O / 9 h / Heating 2: 63 percent / sulfuric acid, (conc.) / 39 h / 100 °C View Scheme
参考文献
Journal of Organic Chemistry USSR (English Translation), , vol. 24, p. 1562 - 1571
Zhurnal Organicheskoi Khimii, , vol. 24, # 8 p. 1731 - 1742
反应条件
borane-THF in tetrahydrofuran 24 h; Heating;
参考文献
Choi, Heung-Jin; Bae, Yoon-Kyung; Kang, Seok-Chan; Sil Park, Yeon; Won Park, Joon; Kim, Woong-Il; Bell, Thomas W
Tetrahedron Letters, 2002 , vol. 43, # 51 p. 9385 - 9389
反应条件
potassium hydroxide in methanol
参考文献
Journal of the American Chemical Society, , vol. 102, p. 6365
反应条件
1: 1.) HO-, 2.) H3O+ 2: BH3*S(CH3)2 3: pyridine / acetonitrile 4: KH / dimethylformamide 5: HBr 6: KOH / methanol View Scheme
参考文献
Journal of the American Chemical Society, , vol. 102, p. 6365
反应条件
1: BH3*S(CH3)2 2: pyridine / acetonitrile 3: KH / dimethylformamide 4: HBr 5: KOH / methanol View Scheme
参考文献
Journal of the American Chemical Society, , vol. 102, p. 6365
反应条件
1: KH / dimethylformamide 2: HBr 3: KOH / methanol View Scheme
参考文献
Journal of the American Chemical Society, , vol. 102, p. 6365
