N-(5-羟基戊基)苄胺合成路线 （共 11 条）
反应条件
sodium tetrahydroborate in ethanol T=0°C; Reduction; 2 h;
参考文献
Zhang, Chuanju; Li, Shijun; Zhang, Jinqiang; Zhu, Kelong; Li, Ning; Huang, Feihe
Organic Letters, 2007 , vol. 9, # 26 p. 5553 - 5556
反应条件
1: With sodium sulfate in dichloromethane T=20°C; 18 h; Inert atmosphere; 2: With sodium tetrahydroborate in ethanol T=0 - 20°C; 6 h;
参考文献
Yin, Jian; Eller, Steffen; Mayeul, Collot; Seeberger, Peter H.
Beilstein Journal of Organic Chemistry, 2012 , vol. 8, p. 2067 - 2071
反应条件
1: With iodine in dichloromethane T=20°C; 2: With sodium hydroxide; dihydrogen peroxide in methanol; water T=20°C; regioselective reaction;
参考文献
Scheideman, Matthew; Wang, Guoqiang; Vedejs, Edwin
Journal of the American Chemical Society, 2008 , vol. 130, # 27 p. 8669 - 8676
反应条件
diisobutylaluminium hydride in tetrahydrofuran T=0 - 20°C; 3 h; Inert atmosphere;
参考文献
Wang, Yu-Huang; Ye, Jian-Liang; Wang, Ai-E; Huang, Pei-Qiang
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 32 p. 6504 - 6511
反应条件
1: H2O; diethyl ether / 20 °C 2: NaBH4 / ethanol / 0 - 20 °C View Scheme
参考文献
Sasano, Yusuke; Nagasawa, Shota; Yamazaki, Mai; Shibuya, Masatoshi; Park, Jaiwook; Iwabuchi, Yoshiharu
Angewandte Chemie - International Edition, 2014 , vol. 53, # 12 p. 3236 - 3240
Angew. Chem., 2014 , vol. 126, # 12 p. 3300 - 3304,5
反应条件
1: H2O; diethyl ether / 20 °C 2: NaBH4 / ethanol / 0 - 20 °C View Scheme
参考文献
Sasano, Yusuke; Nagasawa, Shota; Yamazaki, Mai; Shibuya, Masatoshi; Park, Jaiwook; Iwabuchi, Yoshiharu
Angewandte Chemie - International Edition, 2014 , vol. 53, # 12 p. 3236 - 3240
Angew. Chem., 2014 , vol. 126, # 12 p. 3300 - 3304,5
反应条件
1: hexane 2: tetrahydrofuran / 0.5 h / 20 °C / Inert atmosphere 3: diisobutylaluminium hydride / tetrahydrofuran / 3 h / 0 - 20 °C / Inert atmosphere View Scheme
参考文献
Wang, Yu-Huang; Ye, Jian-Liang; Wang, Ai-E; Huang, Pei-Qiang
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 32 p. 6504 - 6511
反应条件
1: tetrahydrofuran / 0.5 h / 20 °C / Inert atmosphere 2: diisobutylaluminium hydride / tetrahydrofuran / 3 h / 0 - 20 °C / Inert atmosphere View Scheme
参考文献
Wang, Yu-Huang; Ye, Jian-Liang; Wang, Ai-E; Huang, Pei-Qiang
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 32 p. 6504 - 6511
反应条件
hydrogenchloride anschliessende Hydrierung an Raney-Nickel bei 95grad/15 at;
参考文献
Scriabine
Bulletin de la Societe Chimique de France, 1947 , p. 454
反应条件
cis-RuCl2(dppb)(2-aminomethylpyridine); potassium hydroxide in toluene 4 h; Inert atmosphereReflux;
参考文献
Nova, Ainara; Balcells, David; Schley, Nathan D.; Dobereiner, Graham E.; Crabtree, Robert H.; Eisenstein, Odile
Organometallics, 2010 , vol. 29, # 23 p. 6548 - 6558
