2-[(4-甲基苯基)氨基]乙醇合成路线 （共 20 条）
反应条件
copper(l) iodide; 1-(5,6,7,8-tetrahydroquinolin-8-yl)-ethanone; caesium carbonate in N,N-dimethyl-formamide T=25°C; Ullmann condensation; 8 h; Inert atmosphere;
参考文献
Wang, Deping; Ding, Ke
Chemical Communications, 2009 , # 14 p. 1891 - 1893
反应条件
copper(l) chloride; potassium hydroxide T=90°C; 8 h; Neat (no solvent);
参考文献
Yin, Huiqing; Jin, Ming; Chen, Wei; Chen, Chen; Zheng, Likang; Wei, Ping; Han, Shiqing
Tetrahedron Letters, 2012 , vol. 53, # 10 p. 1265 - 1270
反应条件
(α-isobutyryl)cyclohexanone; caesium carbonate; copper(l) iodide in N,N-dimethyl-formamide T=20°C; 20 h;
参考文献
Shafir, Alexandr; Lichtor, Phillip A.; Buchwald, Stephen L.
Journal of the American Chemical Society, 2007 , vol. 129, # 12 p. 3490 - 3491
反应条件
Na-Y zeolite in triglyme (triethylene glycol dimethyl ether) 1.5 h; Heating;
参考文献
Selva, Maurizio; Fabris, Massimo; Lucchini, Vittorio; Perosa, Alvise; Noe, Marco
Organic and Biomolecular Chemistry, 2010 , vol. 8, # 22 p. 5187 - 5198
反应条件
1: in water T=150°C; 0.333333 h; Microwave irradiation; 2: With sodium hydrogencarbonate in water chemoselective reaction;
参考文献
Marzaro, Giovanni; Guiotto, Adriano; Chilin, Adriana
Green Chemistry, 2009 , vol. 11, # 6 p. 774 - 776
反应条件
alkaline solution; water
参考文献
Adams; Segur
Journal of the American Chemical Society, 1923 , vol. 45, p. 789
反应条件
1: benzene 2: alkaline solution; alcohol View Scheme
参考文献
Adams; Segur
Journal of the American Chemical Society, 1923 , vol. 45, p. 789
反应条件
sulfuric acid; iron(II) sulfate; acetic acid T=10 - 20°C; 1.5 h;
参考文献
Zorina, L. N.; Safiev, O. G.; Rakhmankulov, D. L.; Paushkin, Ya. M.
Doklady Chemistry, 1989 , vol. 308, # 4-6 p. 295 - 298
Dokl. Akad. Nauk SSSR Ser. Khim., 1989 , vol. 308, # 5 p. 1150 - 1154
反应条件
18-crown-6 ether; water; potassium hydride 1) THF, 50 to 55 deg C, 40 h, 2) H2O; Yield given. Multistep reaction;
参考文献
Baker, William R.
Journal of Organic Chemistry, 1983 , vol. 48, # 25 p. 5140 - 5143
反应条件
1: 1) N,N'-carbonyldiimidazole / 1) r.t, THF, 30 min, 2) - 50 deg C, THF 2: 1) KH, 18-crown-6, 2) H2O / 1) THF, 50 to 55 deg C, 40 h, 2) H2O View Scheme
参考文献
Baker, William R.
Journal of Organic Chemistry, 1983 , vol. 48, # 25 p. 5140 - 5143
