N-(2-甲氧基苯基)-硫代乙酰胺合成路线 （共 5 条）
反应条件
Lawesson's reagent in toluene T=110°C; 3 h; Inert atmosphere;
参考文献
InterMune, Inc.
Patent: US2011/152246 A1, 2011 ;
Location in patent: Page/Page column 139 ;
反应条件
1: With triethylamine; p-toluenesulfonyl chloride in acetonitrile T=0 - 20°C; Inert atmosphere; 2: With thiourea in acetonitrile 2 h; RefluxInert atmosphere;
参考文献
Liu, Li-Feng; An, Na; Pi, Hong-Jun; Ying, Jun; Du, Wenting; Deng, Wei-Ping
Synlett, 2011 , # 7 p. 979 - 981
反应条件
1: pyridine 2: P2S5 / toluene / 70 °C View Scheme
参考文献
Heitsch, Holger; Wagner, Adalbert; Schoelkens, Bernward A.; Wirth, Klaus
Bioorganic and Medicinal Chemistry Letters, 1999 , vol. 9, # 3 p. 327 - 332
反应条件
1: potassium hexacyanoferrate(III); sodium hydroxide / ethanol; water / 0.83 h / 90 °C 2: AlCl3, aluminium chloride / carbon disulfide / 1.5 h / Reflux View Scheme
参考文献
InterMune, Inc.
Patent: US2011/152246 A1, 2011 ;
反应条件
1: K3Fe(CN)6, aq. NaOH / ethanol / 5 h / 90 °C
2: HI, P(red), CH3CO2H / 10 h / Heating
View Scheme
参考文献
Heitsch, Holger; Wagner, Adalbert; Schoelkens, Bernward A.; Wirth, Klaus
Bioorganic and Medicinal Chemistry Letters, 1999 , vol. 9, # 3 p. 327 - 332
