N-(1-吡啶-4-乙基)-羟胺合成路线 （共 19 条）
反应条件
1: 55 percent / diisopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 2 h / 0 - 20 °C 2: K2CO3 / methanol 3: Pd(Ph3P)4; dimedone; Zn View Scheme
参考文献
Knight, David W.; Leese, Mathew P.
Tetrahedron Letters, 2001 , vol. 42, # 13 p. 2593 - 2595
反应条件
1: K2CO3 / methanol 2: Pd(Ph3P)4; dimedone; Zn View Scheme
参考文献
Knight, David W.; Leese, Mathew P.
Tetrahedron Letters, 2001 , vol. 42, # 13 p. 2593 - 2595
反应条件
1: K2CO3 / methanol 2: Pd(Ph3P)4; dimedone; Zn View Scheme
参考文献
Knight, David W.; Leese, Mathew P.
Tetrahedron Letters, 2001 , vol. 42, # 13 p. 2593 - 2595
反应条件
1: 95 percent / NH2OH*HCl,; pyridine / ethanol / Heating 2: NaCNBH3 / tetrahydrofuran; acetic acid / 24 h / 20 °C View Scheme
参考文献
Katritzky, Alan R.; Cui, Xilin; Long, Qiuhe; Yang, Baozhen; Wilcox, Allan L.; Zhang, Yong-Kang
Organic Preparations and Procedures International, 2000 , vol. 32, # 2 p. 175 - 183
反应条件
hydrogenchloride; sodium cyanoborohydride in methanol; water pH=3 - 4; Inert atmosphere;
参考文献
Pusterla, Ivano; Bode, Jeffrey W.
Angewandte Chemie - International Edition, 2012 , vol. 51, # 2 p. 513 - 516
反应条件
thiophenol; triethylamine in benzene 0.166667 h; Ambient temperaturereducing agent for secondary aliphatic nitro compounds to oximes; Product distribution;
参考文献
Bartra, Marti; Romea, Pedro; Urpi, Felix; Vilarrasa, Jaume
Tetrahedron, 1990 , vol. 46, # 2 p. 587 - 594
反应条件
hydrogenchloride; n-butyllithium 1) ether, hexane, -20 deg C, 2) THF, ether, -40 deg C, 3) MeOH, RT; Multistep reaction;
参考文献
Basha, Anwer; Ratajczyk, James D.; Brooks, Dee W.
Tetrahedron Letters, 1991 , vol. 32, # 31 p. 3783 - 3786
反应条件
1: With diisobutylaluminium hydride in hexane; dichloromethane T=0°C; 3.5 h; Inert atmosphere; 2: With NAF in hexane; dichloromethane; water T=0°C; 0.5 h; Inert atmosphere; regiospecific reaction;
参考文献
Cho, Hidetsura; Sugimoto, Kenji; Iwama, Yusuke; Mitsuhashi, Nakako; Okano, Kentaro; Tokuyama, Hidetoshi
Heterocycles, 2011 , vol. 82, # 2 p. 1633 - 1644
反应条件
1: 94 percent / tetrahydrofuran / 16 h / Heating 2: 43 percent / dicyclohexylcarbodiimide / ethyl acetate / 1 h / 0 °C 3: 21 percent / benzene / 120 h / Irradiation View Scheme
参考文献
Nally; Ordsmith; Procter
Tetrahedron Letters, 1985 , vol. 26, # 34 p. 4107 - 4110
