N-(1-吡啶-4-乙基)-羟胺合成路线 （共 19 条）
反应条件
sodium hydroxide in methanol T=60°C; 0.25 h;
参考文献
Chang, Zen-Yu; Coates, Robert M.
Journal of Organic Chemistry, 1990 , vol. 55, # 11 p. 3464 - 3474
反应条件
hydroxylamine in water; isopropyl alcohol T=140°C; intermolecular Cope-type hydroamination; 72 h;
参考文献
Beauchemin, Andre M.; Moran, Joseph; Lebrun, Marie-Eve; Seguin, Catherine; Dimitrijevic, Elena; Zhang, Lili; Gorelsky, Serge I.
Angewandte Chemie - International Edition, 2008 , vol. 47, # 8 p. 1410 - 1413
反应条件
Benzyltriethylammonium borohydride T=20°C; 0.216667 h; solid-phase conditions;
参考文献
Gopalakrishnan, Mannathusamy; Anandabaskaran, Thirunavukkarasu; Sureshkumar, Purusothaman; Thanusu, Jayaraman; Kumaran, Arumugam K.; Kanagarajan, Vijayakumar
Mendeleev Communications, 2006 , # 1 p. 50 - 51
反应条件
hydroxylamine in water; isopropyl alcohol T=140°C; Cope-type hydroamination; Inert atmosphere; regioselective reaction;
参考文献
Moran, Joseph; Gorelsky, Serge I.; Dimitrijevic, Elena; Lebrun, Marie-Eve; Bedard, Anne-Catherine; Seguin, Catherine; Beauchemin, Andre M.
Journal of the American Chemical Society, 2008 , vol. 130, # 52 p. 17893 - 17906
反应条件
hydrogenchloride; sodium cyanoborohydride in methanol T=25°C; 4.5 h;
参考文献
Ohemeng, Kwasi A.; Podlogar, Brent L.; Nguyen, Van N.; Bernstein, Jeffrey I.; Krause, Heather M.; Hilliard, Jamese J.; Barrett, John F.
Journal of Medicinal Chemistry, 1997 , vol. 40, # 20 p. 3292 - 3296
反应条件
Sn(SPh)2; thiophenol; triethylamine in benzene 0.166667 h; Ambient temperature;
参考文献
Bartra, Marti; Romea, Pedro; Urpi, Felix; Vilarrasa, Jaume
Tetrahedron, 1990 , vol. 46, # 2 p. 587 - 594
反应条件
sodium cyanoborohydride in tetrahydrofuran; acetic acid T=20°C; Reduction; 24 h;
参考文献
Krzeminski, Marek P.; Zaidlewicz, Marek
Tetrahedron Asymmetry, 2003 , vol. 14, # 11 p. 1463 - 1466
反应条件
1: 72 percent / LiAlH4 2: 66 percent / Na2HPO4 / tetrahydrofuran / 3 h / 25 °C 3: 75 percent / 6N NaOH / methanol / 0.25 h / 60 °C View Scheme
参考文献
Chang, Zen-Yu; Coates, Robert M.
Journal of Organic Chemistry, 1990 , vol. 55, # 11 p. 3464 - 3474
反应条件
1: 92 percent 2: 72 percent / LiAlH4 3: 66 percent / Na2HPO4 / tetrahydrofuran / 3 h / 25 °C 4: 75 percent / 6N NaOH / methanol / 0.25 h / 60 °C View Scheme
参考文献
Chang, Zen-Yu; Coates, Robert M.
Journal of Organic Chemistry, 1990 , vol. 55, # 11 p. 3464 - 3474
反应条件
1: 66 percent / Na2HPO4 / tetrahydrofuran / 3 h / 25 °C 2: 75 percent / 6N NaOH / methanol / 0.25 h / 60 °C View Scheme
参考文献
Chang, Zen-Yu; Coates, Robert M.
Journal of Organic Chemistry, 1990 , vol. 55, # 11 p. 3464 - 3474
