2,6-二甲基苯-1-磺酰氯合成路线 （共 7 条）
参考文献
Wyeth
Patent: US2003/144282 A1, 2003 ;
反应条件
chlorine; acetic acid T=0°C;
参考文献
Wagenaar, Anno; Engberts, Jan B. F. N.
Recueil: Journal of the Royal Netherlands Chemical Society, 1982 , vol. 101, # 3 p. 91 - 94
反应条件
(i) NaNO2, aq. HCl, dioxane, (ii) SO2, CuCl2, KCl, benzene; Multistep reaction;
参考文献
Prinsen,A.J.; Cerfontain,H.
Recueil des Travaux Chimiques des Pays-Bas, 1965 , vol. 84, p. 24 - 30
反应条件
n-butyllithium 1.) THF, hexane, -70 deg C, 45 min, 2.) THF, hexane, -70 deg C, 2 h; Yield given. Multistep reaction;
参考文献
Toja, E; Gorini, C; Zirotti, C; Barzaghi, F; Galliani, G
European Journal of Medicinal Chemistry, 1991 , vol. 26, # 4 p. 403 - 413
反应条件
ammonium hydroxide in acetonitrile T=0 - 20°C; 1 h; Inert atmosphere;
参考文献
Patil, Vikas; Kale, Manoj; Raichurkar, Anandkumar; Bhaskar, Brahatheeswaran; Prahlad, Dwarakanath; Balganesh, Meenakshi; Nandan, Santosh; Shahul Hameed
Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 9 p. 2222 - 2225
反应条件
triphenylphosphine in tetrahydrofuran
T=20°C;
参考文献
Kabalka, George W.; Reddy, Marepally Srinivasa; Yao, Min-Liang
Tetrahedron Letters, 2009 , vol. 50, # 52 p. 7340 - 7342
参考文献
Huntress; Autenrieth
Journal of the American Chemical Society, 1941 , vol. 63, p. 3446
