N-苄氧羰基-N-甲基-L-苯丙氨酸合成路线 (共 14 条)
反应条件
potassium hydroxide; tetra(n-butyl)ammonium hydrogensulfate in tetrahydrofuran 0.5 h; Ambient temperature;
参考文献
Tetrahedron, , vol. 55, # 2 p. 313 - 334
反应条件
sodium hydroxide in 1,4-dioxane T=65°C; Hydrolysis; 2 h;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 48, # 1 p. 114 - 119
反应条件
chloro-trimethyl-silane; sodium cyanoborohydride in acetonitrile 0.0833333 h; Ambient temperature;
参考文献
Chemistry Letters, , # 4 p. 299 - 300
反应条件
sodium hydride in tetrahydrofuran T=0 - 20°C;
参考文献
Tetrahedron Asymmetry, , vol. 8, # 23 p. 3947 - 3954
反应条件
sodium hydroxide in acetone
参考文献
Journal of the Chemical Society. Perkin transactions 1, , vol. 5, p. 531 - 540
反应条件
1: CSA / toluene / Heating 2: Et3SiH; CF3COOH / CH2Cl2 View Scheme
参考文献
Helvetica Chimica Acta, , vol. 89, # 11 p. 2611 - 2637
反应条件
1.1: sodium hydride / N,N-dimethyl-formamide / 0.03 h / 0 °C 1.2: 2 h / 20 °C 2.1: lithium hydroxide hydrate / tetrahydrofuran; water / 2 h / 0 - 20 °C View Scheme
参考文献
Asian Journal of Chemistry, , vol. 24, # 1 p. 319 - 322
反应条件
1.1: sodium carbonate / water; ethyl acetate / 0 - 16 °C 2.1: sodium hydride / N,N-dimethyl-formamide / 0.03 h / 0 °C 2.2: 2 h / 20 °C 3.1: lithium hydroxide hydrate / tetrahydrofuran; water / 2 h / 0 - 20 °C View Scheme
参考文献
Asian Journal of Chemistry, , vol. 24, # 1 p. 319 - 322
反应条件
1.1: sodium carbonate / water; ethyl acetate / 0 - 16 °C 2.1: sodium hydride / N,N-dimethyl-formamide / 0.03 h / 0 °C 2.2: 2 h / 20 °C 3.1: lithium hydroxide hydrate / tetrahydrofuran; water / 2 h / 0 - 20 °C View Scheme
参考文献
Asian Journal of Chemistry, , vol. 24, # 1 p. 319 - 322
反应条件
1.1: triethylamine / dichloromethane / 3 h / 0 °C 2.1: (+)-(2S)-2-(3-ethylbenzyl)-2,3-dimethylimidazolidin-4-one; 2,6-lutidinium trifluoromethanesulfonate; 2,6-dimethylpyridine / dimethyl sulfoxide; acetonitrile / 16 h 2.2: 3 h View Scheme
参考文献
Journal of the American Chemical Society, , vol. 135, # 31 p. 11521 - 11524