7-氯-1,3-二氢-3-甲基-5-(o-氯苯基)-2H-1,4-苯并二氮杂卓-2-硫酮合成路线 （共 29 条）
反应条件
tetraphosphorus decasulfide in pyridine
参考文献
Vejdelek; Metys; Protiva
Collection of Czechoslovak Chemical Communications, 1983 , vol. 48, # 1 p. 123-136)
反应条件
1: ZnCl2 / 3 h / 200 - 230 °C 2: diethyl ether / 2 h / 10 °C 3: NH4OH / methanol; diethyl ether / 46 h / 20 °C 4: Lawesson's reagent / toluene / 1.5 h / Heating View Scheme
参考文献
Cortes Cortes; Salazar Franco; Garcia Mellado
Journal of Heterocyclic Chemistry, 2001 , vol. 38, # 3 p. 663 - 669
反应条件
1: ZnCl2 / 3 h / 200 - 230 °C 2: diethyl ether / 2 h / 10 °C 3: NH4OH / methanol; diethyl ether / 46 h / 20 °C 4: Lawesson's reagent / toluene / 1.5 h / Heating View Scheme
参考文献
Cortes Cortes; Salazar Franco; Garcia Mellado
Journal of Heterocyclic Chemistry, 2001 , vol. 38, # 3 p. 663 - 669
反应条件
1: diethyl ether / 2 h / 10 °C 2: NH4OH / methanol; diethyl ether / 46 h / 20 °C 3: Lawesson's reagent / toluene / 1.5 h / Heating View Scheme
参考文献
Cortes Cortes; Salazar Franco; Garcia Mellado
Journal of Heterocyclic Chemistry, 2001 , vol. 38, # 3 p. 663 - 669
反应条件
1: NH4OH / methanol; diethyl ether / 46 h / 20 °C 2: Lawesson's reagent / toluene / 1.5 h / Heating View Scheme
参考文献
Cortes Cortes; Salazar Franco; Garcia Mellado
Journal of Heterocyclic Chemistry, 2001 , vol. 38, # 3 p. 663 - 669
反应条件
1: 1.) 50percent NaH / 1.) mineral oil, DMF, r.t., 20 min; 2.) mineral oil, DMF, r.t., 1 h 2: 40 percent / 10 percent NaOH / H2O / 4 h / 50 °C / further reagent: HCl; further solvent: aq. DMSO; further temperatures and reaction times 3: 29.3 percent / 5percent HCl / methanol; H2O / 2.5 h / -20 °C View Scheme
参考文献
Matsuo; Taniguchi; Ueda
Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 4 p. 1141 - 1150
反应条件
in butan-1-ol 8 h; Heating;
参考文献
Vejdelek, Zdenek; Metys, Jan; Holubek, Jiri; Budesinsky, Milos; Svatek, Emil; et al.
Collection of Czechoslovak Chemical Communications, 1988 , vol. 53, # 1 p. 132 - 144
反应条件
in butan-1-ol 8 h; Heating;
参考文献
Vejdelek, Zdenek; Metys, Jan; Holubek, Jiri; Budesinsky, Milos; Svatek, Emil; et al.
Collection of Czechoslovak Chemical Communications, 1988 , vol. 53, # 1 p. 132 - 144
参考文献
Vejdelek, Zdenek; Metys, Jan; Holubek, Jiri; Budesinsky, Milos; Svatek, Emil; et al.
Collection of Czechoslovak Chemical Communications, 1988 , vol. 53, # 1 p. 132 - 144
反应条件
in butan-1-ol
Heating;
参考文献
Vejdelek; Metys; Protiva
Collection of Czechoslovak Chemical Communications, 1983 , vol. 48, # 1 p. 123-136)
