外型-双环[2.2.1]庚-5-烯-2-甲腈合成路线 （共 40 条）
反应条件
pyridine; p-toluenesulfonyl chloride in water T=22°C; 48 h;
参考文献
Fischer, Walter; Grob, Cyril A.; Sprecher, Georg von; Waldner, Adrian
Helvetica Chimica Acta, 1980 , vol. 63, # 4 p. 928 - 937
反应条件
T=180°C; Diels-Alder Reaction; P=1328.93 - 5931.67 Torr; 5.25 h;
参考文献
PROMERUS, LLC
Patent: US2009/118539 A1, 2009 ;
Location in patent: Page/Page column 9-10 ;
反应条件
ethanol T=70°C; Further byproducts given. Title compound not separated from byproducts;
参考文献
Grob, Cyril A.; Guenther, Bettina; Hanreich, Reinhard; Walder, Adrian
Tetrahedron Letters, 1981 , vol. 22, p. 835 - 838
反应条件
water; triethylamine in 1,4-dioxane T=130°C; 30 h; Further byproducts given;
参考文献
Grob, Cyril A.; Herzfeld, Danielle
Helvetica Chimica Acta, 1982 , vol. 65, # 8 p. 2443 - 2447
反应条件
1) 10 min, 0 deg C; 2) 1 h, 45 deg C-50 deg C;
参考文献
Bischoff, St.; Kasper, F.
Journal fuer Praktische Chemie (Leipzig), 1986 , vol. 328, # 3 p. 449 - 453
反应条件
1: NH3; diethyl ether 2: P2O5 / Erhitzen unter vermindertem Druck View Scheme
参考文献
Boehme et al.
Journal of the American Chemical Society, 1958 , vol. 80, p. 5488,5493
反应条件
1: hydroquinone; aqueous ethanol 2: P2O5 / Erhitzen unter vermindertem Druck View Scheme
参考文献
Boehme et al.
Journal of the American Chemical Society, 1958 , vol. 80, p. 5488,5493
反应条件
perchloric acid; sodium nitrite in water T=20°C; 3 h; pH 3.8; Further byproducts given. Title compound not separated from byproducts;
参考文献
Fermann, Michael; Herpers, Ekkehard; Kirmse, Wolfgang; Neubauer, Regina; Renneke, Franz-Josef; et al.
Chemische Berichte, 1989 , vol. 122, p. 975 - 984
反应条件
1: 4 percent Chromat. / water, triethylamine / dioxane / 312 h / 140 °C 2: 85 percent / CrO3/pyridine complex / CH2Cl2 / 0.5 h 3: 85 percent Chromat. / NaBH4 / diethyl ether; H2O / 2 h 4: 74 percent / pyridine / 72 h / 22 °C 5: 12 percent Chromat. / triethylamine, water / dioxane / 40 h / 130 °C View Scheme
参考文献
Grob, Cyril A.; Herzfeld, Danielle
Helvetica Chimica Acta, 1982 , vol. 65, # 8 p. 2443 - 2447
反应条件
water; triethylamine in 1,4-dioxane T=140°C; 312 h; Further byproducts given;
参考文献
Grob, Cyril A.; Herzfeld, Danielle
Helvetica Chimica Acta, 1982 , vol. 65, # 8 p. 2443 - 2447
