2-肼基-3-硝基-5-三氟甲基吡啶合成路线 （共 3 条）
反应条件
hydrazine hydrate in methanol T=80°C; 12 h;
参考文献
Chun, Kwangwoo; Park, Ji-Seon; Lee, Han-Chang; Kim, Young-Ha; Ye, In-Hea; Kim, Kang-Jeon; Ku, Il-Whea; Noh, Min-Young; Cho, Goang-Won; Kim, Heejaung; Kim, Seung Hyun; Kim, Jeongmin
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 13 p. 3983 - 3987
反应条件
1: sulfuric acid; nitric acid / water / 18 h / 60 °C 2: thionyl chloride / N,N-dimethyl-formamide / 3 h / 110 °C 3: hydrazine hydrate / methanol / 12 h / 80 °C View Scheme
参考文献
Chun, Kwangwoo; Park, Ji-Seon; Lee, Han-Chang; Kim, Young-Ha; Ye, In-Hea; Kim, Kang-Jeon; Ku, Il-Whea; Noh, Min-Young; Cho, Goang-Won; Kim, Heejaung; Kim, Seung Hyun; Kim, Jeongmin
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 13 p. 3983 - 3987
反应条件
1: thionyl chloride / N,N-dimethyl-formamide / 3 h / 110 °C 2: hydrazine hydrate / methanol / 12 h / 80 °C View Scheme
参考文献
Chun, Kwangwoo; Park, Ji-Seon; Lee, Han-Chang; Kim, Young-Ha; Ye, In-Hea; Kim, Kang-Jeon; Ku, Il-Whea; Noh, Min-Young; Cho, Goang-Won; Kim, Heejaung; Kim, Seung Hyun; Kim, Jeongmin
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 13 p. 3983 - 3987
