2,3,5,6-四氟吡啶合成路线 （共 61 条）
反应条件
potassium tetrafluorocobaltate in gaseous matrix T=215 - 225°C; 1.) 3.5-4 h; 2.) 2 h; Further byproducts given;
参考文献
Coe, Paul L.; Holton, Andrew G.; Tatlow, John Colin
Journal of Fluorine Chemistry, 1982 , vol. 21, p. 171 - 190
反应条件
1: in diethyl ether; hexane T=-78 - -60°C; 2 h; 2: With hydrogenchloride in various solvents T=-60 - -40°C; Title compound not separated from byproducts;
参考文献
Abo-Amer, Anwar; Adonin, Nicolay Yu.; Bardin, Vadim V.; Fritzen, Petra; Frohn, Hermann-Josef; Steinberg, Christoph
Journal of Fluorine Chemistry, 2004 , vol. 125, # 11 SPEC. ISS. p. 1771 - 1778
反应条件
XeF2; tetramethyl-ammonium fluoride in dichloromethane T=-60°C; 0.166667 h; Title compound not separated from byproducts.;
参考文献
Abo-Amer, Anwar; Frohn, Hermann-Josef; Steinberg, Christoph; Westphal, Ulrich
Journal of Fluorine Chemistry, 2006 , vol. 127, # 10 SPEC. ISS. p. 1311 - 1323
反应条件
2: steel wool / neat (no solvent) 3: diethyl ether View Scheme
参考文献
Gmelin Handbook: F: PerFHalOrg.5, 4, page 115 - 148
反应条件
zinc in water; N,N-dimethyl-formamide 20 h; Heating;
参考文献
Krasnov; Platonov
Russian Journal of Organic Chemistry, 2000 , vol. 36, # 10 p. 1488 - 1499
反应条件
1: neat (no solvent) 2: catalyst: Pd on active carbon / gaseous matrix View Scheme
参考文献
Gmelin Handbook: F: PerFHalOrg.5, 4, page 115 - 148
反应条件
1: neat (no solvent) 2: diethyl ether View Scheme
参考文献
Gmelin Handbook: F: PerFHalOrg.5, 4, page 115 - 148
反应条件
in tetrahydrofuran T=-20°C;
参考文献
Milner, David J.
Journal of Organometallic Chemistry, 1986 , vol. 302, # 2 p. 147 - 152
反应条件
in tetrahydrofuran T=60°C; 5 h;
参考文献
Breyer, David; Braun, Thomas; Penner, Anna
Dalton Transactions, 2010 , vol. 39, # 32 p. 7513 - 7520
反应条件
2: steel wool / neat (no solvent) 3: catalyst: Pd on active carbon / gaseous matrix View Scheme
参考文献
Gmelin Handbook: F: PerFHalOrg.5, 4, page 115 - 148
