5-硝基-3-羧基苯并异恶唑合成路线 (共 5 条)
反应条件
1: NaH / bis-(2-methoxy-ethyl) ether 2: H2SO4 3: HNO3, H2SO4 View Scheme
参考文献
Kemp,D.S.; Paul,K.G.
Journal of the American Chemical Society, 1975 , vol. 97, p. 7305 - 7312
反应条件
sulfuric acid; nitric acid
参考文献
Kemp,D.S.; Paul,K.G.
Journal of the American Chemical Society, 1975 , vol. 97, p. 7305 - 7312
反应条件
1: H2SO4 2: HNO3, H2SO4 View Scheme
参考文献
Kemp,D.S.; Paul,K.G.
Journal of the American Chemical Society, 1975 , vol. 97, p. 7305 - 7312
反应条件
phosphate buffer in water
T=20°C; antibody 21D8; also for uncatalysed reaction; Rate constant;
参考文献
Lewis, Cristina; Paneth, Piotr; O'Leary, Marion H.; Hilvert, Donald
Journal of the American Chemical Society, 1993 , vol. 115, # 4 p. 1410 - 1413
反应条件
hydrogenchloride; tri-(hydroxymethyl)-methylamine
T=20°C; 25E10 monoclonal antibody; var. monoclonal antibodies, also in the presence of inhibitor: acetamido-1,5-naphthalenedisulfonate; ΔH(excit.), ΔS(excit.); Rate constantThermodynamic data;
参考文献
Backes, Alexander C.; Hotta, Kinya; Hilvert, Donald
Helvetica Chimica Acta, 2003 , vol. 86, # 4 p. 1167 - 1174