1-苄基-1,3-二氢-2H-苯并咪唑-2-酮合成路线 （共 22 条）
反应条件
in dichloromethane
T=20°C;
参考文献
Texas Biotechnology Corporation
Patent: US6723711 B2, 2004 ;
Location in patent: Page column 48 ;
反应条件
trifluorormethanesulfonic acid; water in methanol
3 h; Reflux;
参考文献
UNIVERSITE PAUL CEZANNE-AIX MARSEILLE III
Patent: US2010/120880 A1, 2010 ;
Location in patent: Page/Page column 14-15 ;
US 20100120880 A1
反应条件
potassium phosphate; copper(l) iodide; (2S)-(-)-trans-4-hydroxy-proline in dimethyl sulfoxide
T=70 - 130°C; 10 h;
参考文献
Zou, Benli; Yuan, Qiliang; Ma, Dawei
Organic Letters, 2007 , vol. 9, # 21 p. 4291 - 4294
反应条件
copper(l) iodide; potassium carbonate; L-proline in dimethyl sulfoxide
T=50 - 130°C; 6 h;
参考文献
Zou, Benli; Yuan, Qiliang; Ma, Dawei
Organic Letters, 2007 , vol. 9, # 21 p. 4291 - 4294
参考文献
Cell Pathways, Inc.
Patent: US6420410 B1, 2002 ;
反应条件
potassium hydroxide; [bis(acetoxy)iodo]benzene in methanol
T=0°C; 1 h;
参考文献
Prakash; Batra; Kaur; Sharma; Singh; Moriarty
Synthesis, 2001 , # 4 p. 541 - 543
反应条件
4-Nitrostyrene oxide
T=80 - 90°C; 4 h;
参考文献
Popov; Konstantinchenko
Chemistry of Heterocyclic Compounds, 1996 , vol. 32, # 10 p. 1160 - 1165
反应条件
1: xylene / 18 h / Heating
2: H2 / 10percent Pd/C / methanol / 4 h
3: CaCl2 / 1.5 h / 210 °C
View Scheme
参考文献
Gomez-Parra, Vicente; Sanchez, Felix; Torres, Tomas
Monatshefte fuer Chemie, 1985 , vol. 116, p. 639 - 644
反应条件
1: H2 / 10percent Pd/C / methanol / 4 h
2: CaCl2 / 1.5 h / 210 °C
View Scheme
参考文献
Gomez-Parra, Vicente; Sanchez, Felix; Torres, Tomas
Monatshefte fuer Chemie, 1985 , vol. 116, p. 639 - 644
反应条件
1: 95 percent / 50percent aq. NaOH / triethylbutylammonium chloride / benzene / 1 h / 60 °C
2: 95 percent / conc. hydrochloric acid / H2O / 1 h / 60 °C
View Scheme
参考文献
Vernin, Gaston; Domlog, Hicham; Siv, Chan; Metzger, Jaques; El-Shafei, Ahmed Kamal
Journal of Heterocyclic Chemistry, 1981 , vol. 18, p. 85 - 89
