1: diethoxyphosphoryl-acetic acid ethyl ester With sodium hydride in tetrahydrofuran T=0 - 20°C; 1 h; 2: 8-methyl-8-aza-bicyclo[3.2.1]octan-3-one in tetrahydrofuran T=20°C; Further stages.;

1: (EtO)2P(O)CH2COOEt With sodium hydride in tetrahydrofuran T=-30°C; Metallation; 1 h; 2: 8-methyl-8-aza-bicyclo[3.2.1]octan-3-one Condensation; Horner-Wadsworth-Emmons reaction; Title compound not separated from byproducts;

sodium hydride 1.) THF, 10 deg C, 30 min, 2.) THF, a) RT, 3 h, b) 60 deg C, 4 h; Yield given. Multistep reaction. Yields of byproduct given;