3,3'-二甲基二苯甲酮合成路线 （共 29 条）
反应条件
sodium amalgam; ethanol
参考文献
Coops et al.
Recueil des Travaux Chimiques des Pays-Bas, 1940 , vol. 59, p. 1109,1111
反应条件
NHC-Pd(II)-Im; sodium hydrogencarbonate in water
T=50°C; 12 h; Inert atmosphere;
参考文献
Lin, Xiao-Fang; Li, Yao; Li, Shuang-Yan; Xiao, Zheng-Kang; Lu, Jian-Mei
Tetrahedron, 2012 , vol. 68, # 29 p. 5806 - 5809
反应条件
tetracarbonylbis(μ-chloro)dirhodium(I); di-tert-butyl peroxide; 1,2-bis-(diphenylphosphino)ethane in benzene
T=160°C; 12 h; Inert atmosphere; chemoselective reaction;
参考文献
Yang, Luo; Zeng, Tieqiang; Shuai, Qi; Guo, Xiangyu; Li, Chao-Jun
Chemical Communications, 2011 , vol. 47, # 7 p. 2161 - 2163
反应条件
dicarbonic acid,dimethyl ester; tetrakis(triphenylphosphine) palladium(0) in 1,4-dioxane
T=80°C; 6 h;
参考文献
Yamamoto; Kakino; Narahashi; Shimizu
Bulletin of the Chemical Society of Japan, 2002 , vol. 75, # 6 p. 1333 - 1345
反应条件
1: carbon monoxide With 1,1'-bis-(diphenylphosphino)ferrocene; [RhCl(η2:η2-cycloocta-1,5-diene)]2 in tetrahydrofuran
T=20°C; P=760.051 Torr; 0.166667 h;
2: m-tolylzinc(II) iodide With ethylene dibromide in tetrahydrofuran
T=60°C; 3 h;
参考文献
Kobayashi, Kana; Nishimura, Yugo; Gao, Fuxing; Gotoh, Kazuma; Nishihara, Yasushi; Takagi, Kentaro
Journal of Organic Chemistry, 2011 , vol. 76, # 6 p. 1949 - 1952
反应条件
sodium hydroxide; tetrabutylammomium bromide; dicobalt octacarbonyl; pentacarbonyliron(0) in water; benzene
T=65°C; 24 h;
参考文献
Brunet, Jean-Jacques; Taillefer, Marc
Journal of Organometallic Chemistry, 1990 , vol. 384, p. 193 - 197
反应条件
1: With 3-methylphenylmagnesium chloride in tetrahydrofuran
T=50°C;
2: 18 h; Heating / reflux;
参考文献
ESPERION THERAPEUTICS, INC.
Patent: WO2004/67489 A2, 2004 ;
Location in patent: Page 276-277 ;
反应条件
tetrakis(triphenylphosphine) palladium(0) in 1,4-dioxane
T=80°C; 4 h; Inert atmosphere;
参考文献
Rao, Maddali L. N.; Venkatesh, Varadhachari; Dasgupta, Priyabrata
Tetrahedron Letters, 2010 , vol. 51, # 38 p. 4975 - 4980
反应条件
bis(1,5-cyclooctadiene)nickel (0) in N,N-dimethyl-formamide
T=50°C; 6 h;
参考文献
Goto, Toshio; Onaka, Makoto; Mukaiyama, Teruaki
Chemistry Letters, 1980 , p. 51 - 52
反应条件
tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran
T=60°C; 4 h;
参考文献
Rao, Maddali L. N.; Venkatesh, Varadhachari; Dasgupta, Priyabrata
Tetrahedron Letters, 2010 , vol. 51, # 38 p. 4975 - 4980
