1H-苯并咪唑-2-甲酸合成路线 （共 30 条）
反应条件
1: With water; sodium hydroxide T=0°C; 2 h; 2: With hydrogenchloride in water pH=3;
参考文献
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
Patent: US2009/258876 A1, 2009 ;
Location in patent: Page/Page column 9 ;
反应条件
1: With sodium hydroxide in water T=100°C; 2 h; 2: With potassium permanganate in water T=100°C; 10 h;
参考文献
Xia, Zhengqiang; Wei, Qing; Yang, Qi; Qiao, Chengfang; Chen, Sanping; Xie, Gang; Zhang, Guochun; Zhou, Chunsheng; Gao, Shengli
CrystEngComm, 2013 , vol. 15, # 1 p. 86 - 99
反应条件
carbon dioxide; potassium carbonate in water
参考文献
BASF Aktiengesellschaft
Patent: US5117004 A1, 1992 ;
反应条件
2: 2M sodium hydroxide View Scheme
参考文献
Ramaiah; Grossert; Hooper; Dubey; Ramanatham
Journal of the Indian Chemical Society, 1999 , vol. 76, # 3 p. 140 - 144
反应条件
potassium permanganate; sodium carbonate Oxidation; 1 h; Heating;
参考文献
Ramaiah; Grossert; Hooper; Dubey; Ramanatham
Journal of the Indian Chemical Society, 1999 , vol. 76, # 3 p. 140 - 144
反应条件
potassium permanganate; sodium carbonate Oxidation; 1 h; Heating;
参考文献
Ramaiah; Grossert; Hooper; Dubey; Ramanatham
Journal of the Indian Chemical Society, 1999 , vol. 76, # 3 p. 140 - 144
反应条件
hydrogenchloride; KNO2 T=0°C;
参考文献
Graubaum, Heinz; Martin, Dieter
Journal fuer Praktische Chemie (Leipzig), 1986 , vol. 328, # 4 p. 515 - 521
反应条件
1: H2 / Pd/C / methanol / 20 °C 2: 0.17 h / 240 °C 3: aq. HBr / 48 h / Heating View Scheme
参考文献
Borza, Istvan; Kolok, Sandor; Gere, Aniko; Nagy, Jozsef; Fodor, Laszlo; Galgoczy, Kornel; Fetter, Jozsef; Bertha, Ferenc; Agai, Bela; Horvath, Csilla; Farkas, Sandor; Domany, Gyoergy
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 17 p. 4638 - 4640
反应条件
1: toluene / 10 h / 20 °C 2: H2 / Pd/C / methanol / 20 °C 3: 0.17 h / 240 °C 4: aq. HBr / 48 h / Heating View Scheme
参考文献
Borza, Istvan; Kolok, Sandor; Gere, Aniko; Nagy, Jozsef; Fodor, Laszlo; Galgoczy, Kornel; Fetter, Jozsef; Bertha, Ferenc; Agai, Bela; Horvath, Csilla; Farkas, Sandor; Domany, Gyoergy
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 17 p. 4638 - 4640
反应条件
1: Et3N / CH2Cl2 / 0 - 20 °C 2: toluene / 10 h / 20 °C 3: H2 / Pd/C / methanol / 20 °C 4: 0.17 h / 240 °C 5: aq. HBr / 48 h / Heating View Scheme
参考文献
Borza, Istvan; Kolok, Sandor; Gere, Aniko; Nagy, Jozsef; Fodor, Laszlo; Galgoczy, Kornel; Fetter, Jozsef; Bertha, Ferenc; Agai, Bela; Horvath, Csilla; Farkas, Sandor; Domany, Gyoergy
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 17 p. 4638 - 4640
