5-(吡啶-4-基)-1,3,4-噁二唑-2(3H)-酮合成路线 （共 16 条）
反应条件
1: in water; toluene Cooling with ice; 2: With sodium hydroxide in water
参考文献
Zampieri, Daniele; Mamolo, Maria Grazia; Laurini, Erik; Fermeglia, Maurizio; Posocco, Paola; Pricl, Sabrina; Banfi, Elena; Scialino, Giuditta; Vio, Luciano
Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 13 p. 4693 - 4707
反应条件
potassium phosphate; methyloxirane in water T=20°C;
参考文献
Yoshida; Asai
Yakugaku Zasshi, 1954 , vol. 74, p. 951
Chem.Abstr., 1955 , p. 10938
参考文献
Geistlich Soehne A.G.
Patent: US2758117 , 1954 ;
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Geistlich Soehne A.G.
Patent: DE1001683 , 1954 ;
反应条件
[bis(acetoxy)iodo]benzene in methanol 4 h; Heating;
参考文献
Baumgarten, Henry E.; Hwang, Deng-Ruey; Rao, T. N.
Journal of Heterocyclic Chemistry, 1986 , vol. 23, p. 945 - 949
反应条件
1: potassium cyanate; aqueous acetic acid 2: biphenyl / 240 - 250 °C View Scheme
参考文献
Yan, Xu; Zhou, Shuo; Wang, Yuanqiang; Ge, Zemei; Cheng, Tieming; Li, Runtao
Tetrahedron, 2012 , vol. 68, # 38 p. 7978 - 7983
反应条件
biphenyl T=240 - 250°C;
参考文献
Dornow; Luepfert
Archiv der Pharmazie (Weinheim, Germany), 1955 , vol. 288, p. 311,314
反应条件
1: 77 percent / ethanol 2: 47 percent / Iodosobenzene Diacetate / methanol / 4 h / Heating View Scheme
参考文献
Baumgarten, Henry E.; Hwang, Deng-Ruey; Rao, T. N.
Journal of Heterocyclic Chemistry, 1986 , vol. 23, p. 945 - 949
反应条件
hydrogenchloride; chlorine anschliessend Behandeln mit wss. NaOH;
参考文献
Stempel et al.
Journal of Organic Chemistry, 1955 , vol. 20, p. 412,417
反应条件
1: liquid NH3 2: chlorine; aqueous HCl / anschliessend Behandeln mit wss. NaOH View Scheme
参考文献
Stempel et al.
Journal of Organic Chemistry, 1955 , vol. 20, p. 412,417
反应条件
potassium permanganate; acetic acid
参考文献
Yoshida; Asai
Yakugaku Zasshi, 1954 , vol. 74, p. 951
Chem.Abstr., 1955 , p. 10938
