2-氯-N-[4-氯-2-(2-氟苯基)苯基]乙酰胺合成路线 （共 5 条）
反应条件
N-ethyl-N,N-diisopropylamine in toluene T=10 - 20°C; 3.5 h;
参考文献
Cheng, Pi; Zhang, Quan; Ma, Yun-Bao; Jiang, Zhi-Yong; Zhang, Xue-Mei; Zhang, Feng-Xue; Chen, Ji-Jun
Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 13 p. 3787 - 3789
反应条件
paraformaldehyde in methanol; ammonia; water
参考文献
Hoffmann-La Roche Inc.
Patent: US3996209 A1, 1976 ;
反应条件
1,3,5,7-tetra-azatricyclo[5.1.1.13,5]decane; [HHMTA]Cl in methanol; water Heating; Yields of byproduct given;
参考文献
Clarke, George M.; Lee, J. Barry; Swinbourne, Frederick J.; Williamson, Basil
Journal of Chemical Research, Miniprint, 1980 , # 12 p. 4777 - 4793
反应条件
[HHMTA]Cl in methanol; water Heating;
参考文献
Clarke, George M.; Lee, J. Barry; Swinbourne, Frederick J.; Williamson, Basil
Journal of Chemical Research, Miniprint, 1980 , # 12 p. 4777 - 4793
反应条件
1: hexamine; ammonium chloride / ethanol / 4 h / Heating 2: 66.28 percent / pyridine; P2S5 / 1 h / Heating View Scheme
参考文献
Narayana; Vijaya Raj; Ashalatha; Kumari, N. Suchetha
European Journal of Medicinal Chemistry, 2006 , vol. 41, # 3 p. 417 - 422
