N-乙酰-L-色氨酸甲酯合成路线 （共 24 条）
反应条件
1: ethanethiolic acid With caesium carbonate in N,N-dimethyl-formamide T=20°C; 0.0833333 h; 2: (S)-(-)-tryptophan methyl ester hydrochloride With 1-fluoro-2,4-dinitrobenzene in N,N-dimethyl-formamide T=20°C; 3 h;
参考文献
Crich, David; Sharma, Indrajeet
Angewandte Chemie, International Edition, 2009 , vol. 48, # 13 p. 2355 - 2358
参考文献
Boivin, Jean; Henriet, Eric; Zard, Samir Z.
Journal of the American Chemical Society, 1994 , vol. 116, # 21 p. 9739 - 9740
参考文献
Boivin, Jean; Henriet, Eric; Zard, Samir Z.
Journal of the American Chemical Society, 1994 , vol. 116, # 21 p. 9739 - 9740
反应条件
N-ethyl-N,N-diisopropylamine in dichloromethane 1 h; Inert atmosphere;
参考文献
Ruiz-Rodriguez, Javier; Albericio, Fernando; Lavilla, Rodolfo
Chemistry - A European Journal, 2010 , vol. 16, # 4 p. 1124 - 1127
反应条件
methyl iodide in methanol 24 h; Ambient temperature;
参考文献
Ishida; Nakamura; Irie; Oh-Ishi
Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 8 p. 3237 - 3249
反应条件
triethylamine in dichloromethane T=20°C; Inert atmosphere;
参考文献
Coste, Alexis; Toumi, Mathieu; Wright, Karen; Razafimahaleo, Vanessa; Couty, Francois; Marrot, Jerome; Evano, Gwilherm
Organic Letters, 2008 , vol. 10, # 17 p. 3841 - 3844
反应条件
in methanol; diethyl ether T=0°C;
参考文献
Hashizume, Kazunari; Shimonishi, Yasutsugu
Bulletin of the Chemical Society of Japan, 1981 , vol. 54, # 12 p. 3806 - 3810
反应条件
zinc trifluoromethanesulfonate in chloroform 2 h; Heating;
参考文献
Bucciarelli, Maria; Forni, Arrigo; Moretti, Irene; Prati, Fabio; Torre, Giovanni
Tetrahedron: Asymmetry, 1995 , vol. 6, # 8 p. 2073 - 2080
参考文献
Huang; Niemann
Journal of the American Chemical Society, 1951 , vol. 73, p. 1541,1547
反应条件
4-(N,N-dimethlyamino)pyridine; triethylamine in ethyl acetate T=20°C;
参考文献
Estevao, Monica S.; Carvalho, Luisa C.; Ribeiro, Daniela; Couto, Diana; Freitas, Marisa; Gomes, Ana; Ferreira; Fernandes, Eduarda; Marques, M. Manuel B.
European Journal of Medicinal Chemistry, 2010 , vol. 45, # 11 p. 4869 - 4878
