N,N-dimethyl-formamide; palladium on activated charcoal in tetrahydrofuran; toluene T=25°C; Fukuyama coupling reaction; 22 h;

1: 5-Iodo-pentanoic acid ethyl ester With chloro-trimethyl-silane; ethylene dibromide; zinc in tetrahydrofuran T=55 - 60°C; 0.5 h; 2: m-Chlorthiobenzoesaeure-S-ethylester With 10percent Pd(OH)2/C in tetrahydrofuran; N,N-dimethyl-formamide; toluene T=25°C; Fukuyama coupling; 25 h; Further stages.;

bromine; N,N-dimethyl-formamide; zinc; palladium on activated charcoal in tetrahydrofuran; toluene T=20°C; Fukuyama coupling reaction; 48 h;

bis-triphenylphosphine-palladium(II) chloride in tetrahydrofuran 1 h; Ambient temperature;