2-异丙基-6-甲基-4-嘧啶醇合成路线 （共 8 条）
反应条件
water; propane-1-sulfonic acid; silica gel T=62°C; various catalysts; Rate constantKineticsMechanism;
参考文献
Badley, Rickey D.; Ford, Warren T.
Journal of Organic Chemistry, 1989 , vol. 54, # 23 p. 5437 - 5443
反应条件
triethylamine; Pd(dmba)(py)(OTf) T=25°C; pH=10.80; Kinetics;
参考文献
Lu, Zhong-Lin; Neverov, Alexei A.; Brown, R. Stan
Organic and Biomolecular Chemistry, 2005 , vol. 3, # 18 p. 3379 - 3387
反应条件
water T=40°C; 960 h; E(a); other natural water, pH = 8.0; Rate constantThermodynamic data;
参考文献
Noblet, James A.; Smith, Lynda A.; Suffet
Journal of Agricultural and Food Chemistry, 1996 , vol. 44, # 11 p. 3685 - 3693
反应条件
1: 4-hydroxy-2-isopropyl-6-methyl-pyrimidine With potassium hydroxide in ethanol 2: O,O-diethyl chlorothiophosphate in acetone 48 h; Heating; Further stages.;
参考文献
Churchill, Doreen; Dust, Julian M.; Buncel, Erwin
Canadian Journal of Chemistry, 2007 , vol. 85, # 6 p. 421 - 431
反应条件
1: POCl3 2: ethanol View Scheme
参考文献
Margot; Gysin
Helvetica Chimica Acta, 1957 , vol. 40, p. 1562,1569
反应条件
potassium carbonate in acetone
6 h; Heating;
参考文献
Neelakantan, Parvathi; Rani, Renu; Rahman, M. F.; Bhalerao, U. T.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1985 , vol. 24, p. 1180 - 1181
反应条件
1: POCl3
View Scheme
参考文献
Margot; Gysin
Helvetica Chimica Acta, 1957 , vol. 40, p. 1562,1569
反应条件
trichlorophosphate
T=70°C; 2 h;
参考文献
Sun, Li; Wu, Jie; Zhang, Lingzi; Luo, Min; Sun, Dequn
Molecules, 2011 , vol. 16, # 7 p. 5618 - 5628
