(Z)-8-十二烯基乙酸酯合成路线 （共 53 条）
反应条件
1: DMPA / CH2Cl2 2: 58 percent / NaBH4 / dimethylsulfoxide / 80 °C View Scheme
参考文献
Miyake, Hideyoshi; Yamamura, Kimiaki
Chemistry Letters, 1994 , # 5 p. 897 - 900
反应条件
1: 95 percent / diisobutylaluminum hydride / diethyl ether; toluene / 2 h / -10 °C 2: 90 percent / triphenylphosphine, bromine / CCl4 / 1) 15 deg C, 1 h; 2) room temp., 15 h. 3: 1) cuprous iodide, 2,2'-bipyridyl 2) Mg / 1) abs. THF, 20 deg C, 0.5 h; 2) abs. THF, 2 h at 2 deg C and 15 h at room temp. 4: 1) p-toluenesulfonic acid, water; 2) pyridine / 1) MeOH, room temp., 15 h; 2) room temp., 24 h. View Scheme
参考文献
Odinokov, V. N.; Ishmuratov, G. Yu.; Galeeva, R. I.; Kharisov, R. Ya.; Sokol'skaya, O. V.; at al.
Journal of Organic Chemistry USSR (English Translation), 1988 , vol. 24, # 4 p. 646 - 651
Zhurnal Organicheskoi Khimii, 1988 , vol. 24, # 4 p. 719 - 724
反应条件
1: 90 percent / triphenylphosphine, bromine / CCl4 / 1) 15 deg C, 1 h; 2) room temp., 15 h. 2: 1) cuprous iodide, 2,2'-bipyridyl 2) Mg / 1) abs. THF, 20 deg C, 0.5 h; 2) abs. THF, 2 h at 2 deg C and 15 h at room temp. 3: 1) p-toluenesulfonic acid, water; 2) pyridine / 1) MeOH, room temp., 15 h; 2) room temp., 24 h. View Scheme
参考文献
Odinokov, V. N.; Ishmuratov, G. Yu.; Galeeva, R. I.; Kharisov, R. Ya.; Sokol'skaya, O. V.; at al.
Journal of Organic Chemistry USSR (English Translation), 1988 , vol. 24, # 4 p. 646 - 651
Zhurnal Organicheskoi Khimii, 1988 , vol. 24, # 4 p. 719 - 724
反应条件
1: 85 percent / NaI, zinc dust / bis-(2-methoxy-ethyl) ether / 1.5 h / 65 - 70 °C 2: 95 percent / 5percent aq. HCl / acetone / 6 h / Ambient temperature 3: 95 percent / diisobutylaluminum hydride / diethyl ether; toluene / 2 h / -10 °C 4: 90 percent / triphenylphosphine, bromine / CCl4 / 1) 15 deg C, 1 h; 2) room temp., 15 h. 5: 1) cuprous iodide, 2,2'-bipyridyl 2) Mg / 1) abs. THF, 20 deg C, 0.5 h; 2) abs. THF, 2 h at 2 deg C and 15 h at room temp. 6: 1) p-toluenesulfonic acid, water; 2) pyridine / 1) MeOH, room temp., 15 h; 2) room temp., 24 h. View Scheme
参考文献
Odinokov, V. N.; Ishmuratov, G. Yu.; Galeeva, R. I.; Kharisov, R. Ya.; Sokol'skaya, O. V.; at al.
Journal of Organic Chemistry USSR (English Translation), 1988 , vol. 24, # 4 p. 646 - 651
Zhurnal Organicheskoi Khimii, 1988 , vol. 24, # 4 p. 719 - 724
反应条件
1: 95 percent / 5percent aq. HCl / acetone / 6 h / Ambient temperature 2: 95 percent / diisobutylaluminum hydride / diethyl ether; toluene / 2 h / -10 °C 3: 90 percent / triphenylphosphine, bromine / CCl4 / 1) 15 deg C, 1 h; 2) room temp., 15 h. 4: 1) cuprous iodide, 2,2'-bipyridyl 2) Mg / 1) abs. THF, 20 deg C, 0.5 h; 2) abs. THF, 2 h at 2 deg C and 15 h at room temp. 5: 1) p-toluenesulfonic acid, water; 2) pyridine / 1) MeOH, room temp., 15 h; 2) room temp., 24 h. View Scheme
参考文献
Odinokov, V. N.; Ishmuratov, G. Yu.; Galeeva, R. I.; Kharisov, R. Ya.; Sokol'skaya, O. V.; at al.
Journal of Organic Chemistry USSR (English Translation), 1988 , vol. 24, # 4 p. 646 - 651
Zhurnal Organicheskoi Khimii, 1988 , vol. 24, # 4 p. 719 - 724
反应条件
1: 1) 9-BBN, 2) H2O2, AcONa 2: 85 percent / H2 / Ni-P2 3: 89 percent / pyridine View Scheme
参考文献
Ishmuratov; Ishmuratova; Odinokov; Tolstikov
Chemistry of Natural Compounds, 1997 , vol. 33, # 1 p. 25 - 30
反应条件
1: 94.7 percent / acetonitrile 2: 34 percent / DMSO, NaH / tetrahydrofuran / 0.5 h 3: pyridine View Scheme
参考文献
Horiike; Tanouchi; Hirano
Agricultural and Biological Chemistry, 1980 , vol. 44, # 2 p. 257 - 261
反应条件
1: 34 percent / DMSO, NaH / tetrahydrofuran / 0.5 h 2: pyridine View Scheme
参考文献
Horiike; Tanouchi; Hirano
Agricultural and Biological Chemistry, 1980 , vol. 44, # 2 p. 257 - 261
反应条件
1: 94 percent / LiAlH4 / diethyl ether / 1 h / Heating 2: 95 percent / pyridine View Scheme
参考文献
Aukrust, Audun; Rongved, Pal; Skatteboel, Lars
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1985 , vol. 39, # 4 p. 267 - 272
反应条件
2: 86 percent / hydrazine hydrate, KOH / bis-(2-hydroxy-ethyl) ether / reflux, 1 h; 200 deg C, 3 h 3: 94 percent / LiAlH4 / diethyl ether / 1 h / Heating 4: 95 percent / pyridine View Scheme
参考文献
Aukrust, Audun; Rongved, Pal; Skatteboel, Lars
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1985 , vol. 39, # 4 p. 267 - 272
