乙酰苯-2,3,4,5,6-d5合成路线 （共 17 条）
反应条件
AlCl3, aluminium chloride in carbon disulfide T=5°C; Inert atmosphereReflux;
参考文献
Zhang, Wei; Lou, Shaojie; Liu, Yunkui; Xu, Zhenyuan
Journal of Organic Chemistry, 2013 , vol. 78, # 12 p. 5932 - 5948
反应条件
aluminium trichloride in carbon disulfide 1 h;
参考文献
Kobayashi; Hayashi; Tan; Kishi
Organic letters, 2001 , vol. 3, # 14 p. 2245 - 2248
反应条件
pyridinium chlorochromate in dichloromethane Oxidation; 1 h;
参考文献
Grossi, Loris; Strazzari, Samantha
Journal of Organic Chemistry, 2000 , vol. 65, # 9 p. 2748 - 2754
反应条件
water; palladium dichloride in N,N-dimethyl-formamide T=20°C; Wacker reaction; Title compound not separated from byproducts;
参考文献
Wright, Joseph A.; Gaunt, Matthew J.; Spencer, Jonathan B.
Chemistry - A European Journal, 2006 , vol. 12, # 3 p. 949 - 955
反应条件
1: With neopentylmagnesium bromide; 1,3-bis(2,4,6-trimethylphenyl)imidazolinium chloride; cobalt(II) dibromide in tetrahydrofuran T=20°C; 2: With water-d2 in tetrahydrofuran T=20°C; 3: With hydrogenchloride; water in tetrahydrofuran T=20°C;
参考文献
Gao, Ke; Lee, Pin-Sheng; Long, Chong; Yoshikai, Naohiko
Organic Letters, 2012 , vol. 14, # 16 p. 4234 - 4237
反应条件
1: With neopentylmagnesium bromide; 1,3-bis(2,4,6-trimethylphenyl)imidazolinium chloride; cobalt(II) dibromide in tetrahydrofuran T=20°C; 2: With hydrogenchloride; water in tetrahydrofuran T=20°C; 1 h;
参考文献
Gao, Ke; Lee, Pin-Sheng; Long, Chong; Yoshikai, Naohiko
Organic Letters, 2012 , vol. 14, # 16 p. 4234 - 4237
反应条件
1: 65 percent / potassium tert-butoxide / tetrahydrofuran / 0.5 h 2: H2O / PdCl2 / dimethylformamide / 20 °C View Scheme
参考文献
Wright, Joseph A.; Gaunt, Matthew J.; Spencer, Jonathan B.
Chemistry - A European Journal, 2006 , vol. 12, # 3 p. 949 - 955
反应条件
1.1: n-BuLi / hexane; tetrahydrofuran 1.2: 81.4 percent / tetrahydrofuran; hexane / 0.58 h / 20 °C 2.1: 61.8 percent / pyridinium chlorochromate / CH2Cl2 / 1 h View Scheme
参考文献
Grossi, Loris; Strazzari, Samantha
Journal of Organic Chemistry, 2000 , vol. 65, # 9 p. 2748 - 2754
反应条件
AlCl3, aluminium chloride in 1,2-dichloro-ethane T=20°C; Friedel-Crafts Acylation; 4.5 h; Inert atmosphereSchlenk technique; Kinetics;
参考文献
Huang, Zhiliang; Jin, Liqun; Han, Heyou; Lei, Aiwen
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 11 p. 1810 - 1814
反应条件
1: LiAlH4 2: dehydratisation View Scheme
参考文献
Nakaoki, Takahiko; Kobayashi, Masamichi
Journal of Molecular Structure, 1991 , vol. 242, # 1 p. 315 - 331
