N-甲基-3,3-二苯基丙胺合成路线 （共 5 条）
反应条件
trifluorormethanesulfonic acid
参考文献
Klumpp; Aguirre; Sanchez Jr.; de Leon
Organic letters, 2001 , vol. 3, # 17 p. 2781 - 2784
参考文献
Recordati S.A., Chemical and Pharmaceutical Company
Patent: US4806534 A1, 1989 ;
反应条件
in xylene 8.5 h; Heating;
参考文献
Leonardi, Amedeo; Motta, Gianni; Pennini, Renzo; Testa, Rodolfo; Sironi, Giorgio; Catto, Alberto; Cerri, Alberto; Zappa, Marco; Bianchi, Giorgio; Nardi, Dante
European Journal of Medicinal Chemistry, 1998 , vol. 33, # 5 p. 399 - 420
反应条件
1: 80 percent / xylene / 8.5 h / Heating 2: 72 percent / toluene / 2 h / 80 °C 3: 91 percent / HCl / CHCl3 / 15 °C 4: propan-2-ol / Heating View Scheme
参考文献
Leonardi, Amedeo; Motta, Gianni; Pennini, Renzo; Testa, Rodolfo; Sironi, Giorgio; Catto, Alberto; Cerri, Alberto; Zappa, Marco; Bianchi, Giorgio; Nardi, Dante
European Journal of Medicinal Chemistry, 1998 , vol. 33, # 5 p. 399 - 420
反应条件
1: in xylene 10 h; Heating / refluxBasic conditions; 2: With hydrogenchloride in diethyl ether; xylene 24 h;
参考文献
MOTIVAN LTD.
Patent: WO2006/59332 A1, 2006 ;
Location in patent: Example 3 ;
