5,6-二甲氧基吲哚-2-羧酸甲酯合成路线 （共 16 条）
反应条件
Rh2(pbf)4 in toluene T=40°C; 16 h;
参考文献
Bonnamour, Julien; Bolm, Carsten
Organic Letters, 2011 , vol. 13, # 8 p. 2012 - 2014
反应条件
MoO2Cl2(dmf)2; triphenylphosphine in toluene T=200°C; Cadogan reaction; 1 h; Microwave irradiation;
参考文献
Huleatt, Paul B.; Lau, Jacelyn; Chua, Sheena; Tan, Yun Lei; Duong, Hung Anh; Chai, Christina L.L.
Tetrahedron Letters, 2011 , vol. 52, # 12 p. 1339 - 1342
反应条件
in m-xylene T=140°C; 0.416667 h;
参考文献
The Scripps Research Institute
Patent: US2005/26987 A1, 2005 ;
Location in patent: Page 20 ;
反应条件
1: 25 percent / sodium methoxide / methanol / 4 h / -10 °C 2: 88 percent / Rh2(pbf)4 / toluene / 16 h / 40 °C View Scheme
参考文献
Coowar, Djalil; Bouissac, Julien; Hanbali, Mazen; Paschaki, Marie; Mohier, Eliane; Luu, Bang
Journal of Medicinal Chemistry, 2004 , vol. 47, # 25 p. 6270 - 6282
反应条件
bis-triphenylphosphine-palladium(II) chloride; N-ethyl-N,N-diisopropylamine; triphenylphosphine in tetrahydrofuran T=110°C; P=7600.51 Torr; 20 h; Autoclave;
参考文献
Vieira, Tiago O.; Meaney, Laura A.; Shi, Yong-Ling; Alper, Howard
Organic Letters, 2008 , vol. 10, # 21 p. 4899 - 4901
反应条件
copper(I) oxide; caesium carbonate in 1-methyl-pyrrolidin-2-one T=100°C; 16 h; Inert atmosphereSealed tube;
参考文献
Zhu, Zhiqiang; Yuan, Jiangjun; Zhou, Yirong; Qin, Yang; Xu, Jingshi; Peng, Yiyuan
European Journal of Organic Chemistry, 2014 , vol. 2014, # 3 p. 511 - 514
反应条件
in xylene T=140°C; 2 h;
参考文献
Huleatt, Paul B.; Choo, Sze Shiong; Chua, Sheena; Chai, Christina L.L.
Tetrahedron Letters, 2008 , vol. 49, # 36 p. 5309 - 5311
参考文献
Gauden; Pezzella; Panzella; Neves-Petersen; Skovsen; Petersen; Mullen; Napolitano; D'Ischia; Sundstroem
Journal of the American Chemical Society, 2008 , vol. 130, # 50 p. 17038 - 17043
反应条件
1: sodium hydride / tetrahydrofuran; mineral oil / 1 h / Reflux 2: MoO2Cl2(dmf)2; triphenylphosphine / toluene / 1 h / 200 °C / Microwave irradiation View Scheme
参考文献
Huleatt, Paul B.; Lau, Jacelyn; Chua, Sheena; Tan, Yun Lei; Duong, Hung Anh; Chai, Christina L.L.
Tetrahedron Letters, 2011 , vol. 52, # 12 p. 1339 - 1342
反应条件
in xylene T=140 - 145°C; Yield given. Yields of byproduct given;
参考文献
Sreenivasa Reddy; Cook, James M.
Tetrahedron Letters, 1994 , vol. 35, # 30 p. 5413 - 5416
