3,7-Diazabicyclo[3.3.1]Nonane合成路线 （共 8 条）
反应条件
in dichloromethane T=-20°C;
参考文献
Cui, Huiling; Goddard, Richard; Poerschke, Klaus-Richard
Journal of Physical Organic Chemistry, 2012 , vol. 25, # 10 p. 814 - 827
反应条件
trifluoroacetic acid in dichloromethane
T=20°C; 2 h;
参考文献
Haridas; Sadanandan, Sandhya; Sharma, Yogesh K.; Chinthalapalli, Srinivas; Shandilya, Ashutosh
Tetrahedron Letters, 2012 , vol. 53, # 6 p. 623 - 626
反应条件
hydrogen; acetic acid; palladium on activated charcoal in methanol
Hydrogenolysis; 18 h;
参考文献
Spieler, Jan; Huttenloch, Oliver; Waldmann, Herbert
European Journal of Organic Chemistry, 2000 , # 3 p. 391 - 399
反应条件
1: With potassium hydroxide in ethanol
12 h; Heating;
2: 20 h; Heating;
参考文献
Miyahara; Goto; Inazu
Synthesis, 2001 , # 3 p. 364 - 366
反应条件
1,4-dioxane; nickel
T=150°C; P=88260.9 Torr; Hydrogenation;
参考文献
Bohlmann et al.
Justus Liebigs Annalen der Chemie, 1954 , vol. 587, p. 162,167
Chemische Berichte, 1956 , vol. 89, p. 792,796
反应条件
1: With chloroformic acid ethyl ester
2: With potassium hydroxide
参考文献
Cui, Huiling; Goddard, Richard; Poerschke, Klaus-Richard
Organometallics, 2011 , vol. 30, # 22 p. 6241 - 6252
反应条件
1: palladium 10 on activated carbon; hydrogen / ethanol / 4 h
2: trifluoroacetic acid / dichloromethane / 2 h / 20 °C
View Scheme
参考文献
Haridas; Sadanandan, Sandhya; Sharma, Yogesh K.; Chinthalapalli, Srinivas; Shandilya, Ashutosh
Tetrahedron Letters, 2012 , vol. 53, # 6 p. 623 - 626
反应条件
1.1: hydrazine hydrate / diethylene glycol / 0.17 h / 60 °C
1.2: 8 h / 160 °C
2.1: palladium 10 on activated carbon; hydrogen / ethanol / 4 h
3.1: trifluoroacetic acid / dichloromethane / 2 h / 20 °C
View Scheme
参考文献
Haridas; Sadanandan, Sandhya; Sharma, Yogesh K.; Chinthalapalli, Srinivas; Shandilya, Ashutosh
Tetrahedron Letters, 2012 , vol. 53, # 6 p. 623 - 626
