(R)-(-)-1-氨基-2-丙醇合成路线 (共 18 条)
反应条件
cyclohexenon in various solvent(s) T=154°C; 9 h;
参考文献
Hashimoto, Mitsunori; Eda, Yutaka; Osanai, Yasutomo; Iwai, Toshiaki; Aoki, Seiichi
Chemistry Letters, 1986 , p. 893 - 896
反应条件
sodium tetrahydroborate; nickel dichloride in N,N-dimethyl-formamide T=20°C;
参考文献
Laval, Gilles; Golding, Bernard T.
Synlett, 2003 , # 4 p. 542 - 546
反应条件
ammonia in methanol; water T=15 - 20°C; Title compound not separated from byproducts;
参考文献
Guangyou, Zhang; Yuquing, Liao; Zhaohui, Wang; Nohira, Hiroyuki; Hirose, Takuji
Tetrahedron Asymmetry, 2003 , vol. 14, # 21 p. 3297 - 3300
反应条件
lithium aluminium tetrahydride
参考文献
Wolf et al.
Journal of the American Chemical Society, 1950 , vol. 72, p. 2820
反应条件
hydrogenchloride T=135°C;
参考文献
Levene; Haller
Journal of Biological Chemistry, 1925 , vol. 65, p. 53
反应条件
ueber (R)-1-Benzylamino-propan-2-ol;
参考文献
Yahiro, Nobuhide
Chemistry Letters, 1982 , p. 1479 - 1480
Title/Abstract Full Text Show Details
Gelber, Loren R.; Karger, Barry L.; Neumeyer, John L.; Feibush, Binyamin
Journal of the American Chemical Society, 1984 , vol. 106, # 25 p. 7729 - 7734
反应条件
palladium 10 on activated carbon; ammonium formate in methanol 4 h; RefluxInert atmosphere;
参考文献
Duthion, Beranger; Metro, Thomas-Xavier; Gomez Pardo, Domingo; Cossy, Janine
Tetrahedron, 2009 , vol. 65, # 33 p. 6696 - 6706
反应条件
T=120°C; 5 h; Inert atmosphere;
参考文献
EPITECH GROUP S.r.L.; DELLA VALLE, Francesco; DELLA VALLE maria Federica; DI MARZO, Vincenzo; CUZZOCREA, Salvatore
Patent: WO2013/121449 A1, 2013 ;
Location in patent: Page/Page column 20; 21 ;
参考文献
Pfizer Inc.
Patent: US6201007 B1, 2001 ;
反应条件
in methanol; water Kinetics;
参考文献
Grigorean; Lebrilla
Analytical Chemistry, 2001 , vol. 73, # 8 p. 1684 - 1691