5-(4-氯苯基)吡咯烷-2-酮合成路线 （共 2 条）
反应条件
1: With ammonium acetate in methanol T=25°C; 1 h; 2: With sodium cyanoborohydride in methanol 18 h; Reflux;
参考文献
ARES TRADING S.A.; WHITTAKER, Ben; STEELE, Chris; HARDICK, David; MITCHELL, Dale; POMEL, Vincent; QUATTROPANI, Anna; BEHER, Dirk
Patent: WO2014/12614 A1, 2014 ;
Location in patent: Page/Page column 33 ;
反应条件
1.1: triethylamine; 4-(N,N-dimethlyamino)pyridine / dichloromethane / 18 h / 0 - 25 °C 2.1: ammonium acetate / methanol / 1 h / 25 °C 2.2: 18 h / |Reflux View Scheme
参考文献
ARES TRADING S.A.; WHITTAKER, Ben; STEELE, Chris; HARDICK, David; MITCHELL, Dale; POMEL, Vincent; QUATTROPANI, Anna; BEHER, Dirk
Patent: WO2014/12614 A1, 2014 ;
