L-谷氨酸双苄酯对甲苯磺酸盐合成路线 （共 7 条）
反应条件
in benzene 7 h; Reflux;
参考文献
Deng, Guanghui; Liu, Zhiguo; Ye, Fei; Luo, Xiaomin; Zhu, Weiliang; Shen, Xu; Liu, Hong; Jiang, Hualiang
European Journal of Medicinal Chemistry, 2008 , vol. 43, # 12 p. 2699 - 2716
反应条件
toluene-4-sulfonic acid in benzene Heating;
参考文献
Mishin, M. A.; Guseva, E. G.; Dumpis, M. A.; Shabanov, P. D.; Piotrovskii, L. B.
Pharmaceutical Chemistry Journal, 1991 , vol. 25, # 4 p. 246 - 248
Khimiko-Farmatsevticheskii Zhurnal, 1991 , vol. 25, # 4 p. 24 - 26
反应条件
1: 85 percent / TEA, isobutyl chloroformate / tetrahydrofuran / 4 h / Ambient temperature 2: 72 percent / H2 / 10percent Pd-C / methanol; acetic acid / 10 h View Scheme
参考文献
Gaur, R. K.; Chauhan, V. S.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1988 , vol. 27, # 1-12 p. 405 - 408
反应条件
1: 93 percent / DCC 2: 90 percent / H2 / Pd black / aq. acetic acid; methanol / 5 h View Scheme
参考文献
Noda, Kosaku; Igata, Keiko; Horikawa, Yoshiko; Fujii, Hisao
Agricultural and Biological Chemistry, 1980 , vol. 44, # 10 p. 2419 - 2424
反应条件
1: 1.) CuSO4*5H2O, H2O, 2.) EDTA, H2O / 1.) EtOH, 32 deg C, 60 min, 2.) EtOH, 100 deg C 2: H2SO4 / dioxane 3: Et3N / dioxane / 0 °C 4: 100 percent / H2 / Pd/C / ethanol View Scheme
参考文献
Adlington, Robert M.; Baldwin, Jack E.; Catterick, David; Pritchard, Garcth J.
Journal of the Chemical Society - Perkin Transactions 1, 1999 , # 8 p. 855 - 866
反应条件
ethylenediaminetetraacetic acid; water; copper(II) sulfate 1.) EtOH, 32 deg C, 60 min, 2.) EtOH, 100 deg C; Yield givenMultistep reaction;
参考文献
Adlington, Robert M.; Baldwin, Jack E.; Catterick, David; Pritchard, Garcth J.
Journal of the Chemical Society - Perkin Transactions 1, 1999 , # 8 p. 855 - 866
反应条件
triethylamine in dichloromethane
T=20°C; 19 h;
参考文献
Brimble, Margaret A.; Trotter, Nicholas S.; Harris, Paul W.R.; Sieg, Frank
Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 2 p. 519 - 532
