2-氨基-3,5-二氯苯甲酸合成路线 （共 38 条）
反应条件
hydrogen; rhenium; nickel in methanol T=20°C;
参考文献
VITAE PHARMACEUTICALS, INC.
Patent: WO2009/108332 A1, 2009 ;
Location in patent: Page/Page column 54 ;
WO 2009/108332 A1
反应条件
hydrogenchloride; chlorine in water T=35°C;
参考文献
Wu, Jian; Bai, Song; Yue, Min; Luo, Li-Jun; Shi, Qin-Cai; Ma, Juan; Du, Xian-Li; Kang, Sheng-Hong; Hu, Deyu; Yang, Song
Chemical Papers, 2014 , vol. 68, # 7 p. 969 - 975
反应条件
hydrogenchloride; dihydrogen peroxide in water; N,N-dimethyl-formamide T=45 - 50°C; 15 h;
参考文献
Borodina
Journal of applied chemistry of the USSR, 1986 , vol. 59, # 5 pt 2 p. 1087 - 1089
反应条件
1: nitric acid / 0 °C 2: aqueous potassium permanganate solution 3: iron (II)-sulfate; aqueous ammonia View Scheme
参考文献
Asinger
Monatshefte fuer Chemie, 1933 , vol. 63, p. 385,390
反应条件
1: nitric acid / 70 - 80 °C 2: iron (II)-sulfate; aqueous ammonia View Scheme
参考文献
Asinger
Monatshefte fuer Chemie, 1933 , vol. 63, p. 385,390
反应条件
1: aqueous potassium permanganate solution 2: iron (II)-sulfate; aqueous ammonia View Scheme
参考文献
Asinger
Monatshefte fuer Chemie, 1933 , vol. 63, p. 385,390
反应条件
para-aminobenzoic acid potassium salt
参考文献
Suesse, M.; Johne, S.
Journal fuer Praktische Chemie (Leipzig), 1984 , vol. 326, # 6 p. 1027 - 1033
反应条件
1: potassium permanganate; tetrabutylammomium bromide 2: hydrogen; palladium on activated charcoal View Scheme
参考文献
Dong, Kui-Kui; Zhou, Hua-Hong; Guo, A-Rong; Chen, Tian; Wang, Yu-Liang
Asian Journal of Chemistry, 2013 , vol. 25, # 2 p. 1039 - 1042
反应条件
dihydrogen peroxide; sodium methylate 1.) 0-10 deg C 2.) room temperature, 30 min; Yield given. Multistep reaction;
参考文献
Reissenweber, Gernot; Mangold, Dietrich
Angewandte Chemie, 1981 , vol. 93, # 10 p. 914 - 915
反应条件
durch Oxydation und Verseifung des Reaktionsproduktes;
参考文献
Hoechster Farbw.
Patent: DE152484 ;
