2-氯-3-硝基-4-氨基吡啶合成路线 （共 11 条）
反应条件
1: With sulfuric acid T=20 - 100°C; 1 h; 2: With ammonia in water T=20°C; pH=3;
参考文献
Yin, Xueqiang; Schneller, Stewart W
Nucleosides, nucleotides and nucleic acids, 2004 , vol. 23, # 1-2 p. 67 - 76
反应条件
ammonia in ethanol T=20°C; 96 h;
参考文献
Boehringer Ingelheim Pharma GmbH Co. KG
Patent: US2005/20574 A1, 2005 ;
Location in patent: Page/Page column 16 ;
反应条件
1: With sulfuric acid; nitric acid in water T=0 - 5°C; 0.5 h; 2: With ammonia; water pH=~ 3; 3: With sulfuric acid; ammonia; water more than 3 stages;
参考文献
Yoo, Euna; Crall, Breanna M.; Balakrishna, Rajalakshmi; Malladi, Subbalakshmi S.; Fox, Lauren M.; Hermanson, Alec R.; David, Sunil A.
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 38 p. 6526 - 6545
反应条件
potassium permanganate; ammonia T=-33°C; 5 h;
参考文献
Seko, Shinzo; Miyake, Kunihito
Chemical Communications, 1998 , # 15 p. 1519 - 1520
反应条件
methoxylamine hydrochloride; potassium tert-butylate; zinc(II) chloride in various solvent(s) Ambient temperature;
参考文献
Seko, Shinzo; Miyake, Kunihito
Chemical Communications, 1998 , # 15 p. 1519 - 1520
反应条件
1: nitric acid; sulfuric acid / 0.5 h / 0 °C 2: sulfuric acid / 1.5 h / 75 °C View Scheme
参考文献
Talik; Plazek
Roczniki Chemii, 1956 , vol. 30, p. 1139,1144
Chem.Abstr., 1957 , p. 12089
参考文献
Talik; Plazek
Roczniki Chemii, 1956 , vol. 30, p. 1139,1144
Chem.Abstr., 1957 , p. 12089
反应条件
hydrogen; nickel in ethanol T=20°C; P=760.051 Torr; 4 h;
参考文献
UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC.
Patent: WO2007/47793 A2, 2007 ;
Location in patent: Page/Page column 87 ;
参考文献
Talik; Plazek
Roczniki Chemii, 1956 , vol. 30, p. 1139,1145
Chem.Abstr., <1957> 12089
反应条件
water in dimethyl sulfoxide T=130°C; 4 h;
参考文献
Boehringer Ingelheim Pharma GmbH Co. KG
Patent: US2005/20574 A1, 2005 ;
Location in patent: Page/Page column 16 ;
