(2,6-二甲氧基苯基)锂合成路线 （共 25 条）
参考文献
Pedersen,J.A.; Torssell,K.
Acta Chemica Scandinavica (1947-1973), 1971 , vol. 25, p. 3151 - 3162
参考文献
Gmelin Handbook: B: B-Verb.13, 4.7.2.6, page 219 - 226
反应条件
1-azidostyrene in tetrahydrofuran 2 h; from -78 deg.C to room temp.;
参考文献
Tetrahedron Letters, , vol. 23, # 7 p. 699 - 702
反应条件
in diethyl ether
24 h; Ambient temperature;
参考文献
Wada, Masanori; Natsume, Satoko; Suzuki, Shinobu; Uo, Akira; Nakamura, Michiaki; Hayase, Shuichi; Erabi, Tatsuo
Journal of Organometallic Chemistry, 1997 , vol. 548, # 2 p. 223 - 227
参考文献
Becht, Jean-Michel; Gissot, Arnaud; Wagner, Alain; Mioskowski, Charles
Tetrahedron Letters, 2004 , vol. 45, # 51 p. 9331 - 9333
反应条件
n-butyllithium in ethylene glycol dimethyl ether
参考文献
Hoechst-Roussel Pharmaceuticals Inc.
Patent: US4579981 A1, 1986 ;
反应条件
1: tetrahydrofuran / 3 h / -35 °C
2: tetrabutyl ammonium fluoride / tetrahydrofuran / 3 h / 25 °C / Inert atmosphere
View Scheme
参考文献
Diemer, Vincent; Garcia, Juan Sanz; Leroux, Frederic R.; Colobert, Francoise
Journal of Fluorine Chemistry, 2012 , vol. 134, p. 146 - 155
反应条件
1: tetrahydrofuran / 3 h / -35 °C
2: tetrabutyl ammonium fluoride / tetrahydrofuran / 16 h / 25 °C / Inert atmosphere
View Scheme
参考文献
Diemer, Vincent; Garcia, Juan Sanz; Leroux, Frederic R.; Colobert, Francoise
Journal of Fluorine Chemistry, 2012 , vol. 134, p. 146 - 155
参考文献
Wada, Masanori; Hidashizaki, Shogo
Journal of the Chemical Society, Chemical Communications, 1984 , # 7 p. 482 - 483
反应条件
1.1: N,N-diethylphosphoramidous dichloride / toluene / 2 h / 20 °C
2.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / 0 - 25 °C
2.2: 3 h / 0 - 25 °C
View Scheme
参考文献
Neuwald, Boris; Caporaso, Lucia; Cavallo, Luigi; Mecking, Stefan
Journal of the American Chemical Society, 2013 , vol. 135, # 3 p. 1026 - 1036
