5-(4-羟基苯基)-5-苯基海因合成路线 （共 8 条）
反应条件
aluminium trichloride in various solvent(s) T=20°C; 2 h;
参考文献
Riedner, Jens; Vogel, Pierre
Tetrahedron Asymmetry, 2004 , vol. 15, # 17 p. 2657 - 2660
反应条件
potassium cyanide in ethanol; water T=120°C; 18 h;
参考文献
Riedner, Jens; Vogel, Pierre
Tetrahedron Asymmetry, 2004 , vol. 15, # 17 p. 2657 - 2660
参考文献
Butler
Journal of Pharmacology and Experimental Therapeutics, 1957 , vol. 119, p. 1,2
参考文献
Nitz et al.
Arzneimittel Forschung, 1955 , vol. 5, p. 357,358
反应条件
safrazine; microsomal cyt P-450 T=37°C; inhibitory effect of safrazine;
参考文献
Kasuya; Mamada; Baba; Matsukura
Journal of Pharmaceutical Sciences, 1985 , vol. 74, # 5 p. 503 - 507
反应条件
dihydrogen peroxide; iron powder; 5'-Adenylphosphoric acid T=37°C; Product distribution; Further Variations:Reagents;
参考文献
Mays, Dennis C.; Pawluk, Lew J.; Apseloff, Glen; Davis, W. Bruce; She, Zhi-Wu; Sagone, Arthur L.; Gerber, Nicholas
Biochemical Pharmacology, 1995 , vol. 50, # 3 p. 367 - 380
参考文献
Moustafa; El-Emam; Subbagh; Sharaf El-Din
Arzneimittel-Forschung/Drug Research, 1990 , vol. 40, # 10 p. 1076 - 1078
反应条件
sodium hydroxide; (-)-Brucine in methanol
Heating;
参考文献
Riedner, Jens; Vogel, Pierre
Tetrahedron Asymmetry, 2004 , vol. 15, # 17 p. 2657 - 2660
