1: t-butyl 2-(diethoxyphosphoryl)acetate With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 2: pyridine-2-carbaldehyde in tetrahydrofuran; hexane T=-78 - 20°C; Wittig reaction; Further stages.;
参考文献
Bull, Steven D.; Davies, Stephen G.; Fox, David J.; Gianotti, Massimo; Kelly, Peter M.; Pierres, Camille; Savory, Edward D.; Smith, Andrew D.
Journal of the Chemical Society. Perkin Transactions 1, 2002 , # 16 p. 1858 - 1868