1: 4-iodoacetophenone oxime With 4-cyano-3-fluorophenoxymethyl-Merrifield's resin; potassium tert-butylate in tetrahydrofuran; dimethyl sulfoxide T=55°C; 4 h; 2: 3,4,5-trimethoxyphenylboronic acid With sodium carbonate; tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran; water T=55°C; Suzuki coupling; 24 h; 3: With trifluoroacetic acid in water T=55°C; 2 h; Further stages.;

1: With hydroxymethylpolystyrene resin-CH2OCO2-N-imidazol in 1,2-dichloro-ethane T=60°C; 72 h; 2: With trifluoroacetic acid in dichloromethane T=35°C; Beckmann rearrangement; 16 h;