4-羟基噻吩并[3,2-C]吡啶合成路线 (共 13 条)
反应条件
trichlorophosphate 2.5 h; Heating;
参考文献
New, James S.; Christopher, William L.; Yevich, Joseph P.; Butler, Rhett; Schlemmer, R. Francis; et al.
Journal of Medicinal Chemistry, 1989 , vol. 32, # 6 p. 1147 - 1156
反应条件
1: 85 percent / POCl3 / 2.5 h / Heating 2: 54 percent / ethanol / 24 h / 120 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 32, # 6 p. 1147 - 1156
反应条件
1: 1.) sodium hydride / 1.) benzene, 65 deg C, 2.) reflux, 48 h 2: 87 percent / sodium hydroxide / H2O / Heating View Scheme
参考文献
New; Christopher; Jass
Journal of Organic Chemistry, 1989 , vol. 54, # 4 p. 990 - 992