Z-ALA-PHE-OH合成路线 （共 18 条）
反应条件
triethylamine in tetrahydrofuran; water
0.0833333 h; Ambient temperatureother 3-acyl-1,3-thiazolidine-2-thione;
参考文献
Nagao, Yoshimitsu; Miyasaka, Tadayo; Seno, Kaoru; Fujita, Eiichi; Shibata, Daisuke; Doi, Etsushiro
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , p. 2439 - 2446
反应条件
potassium chloride; water; papain in N,N-dimethyl-formamide
T=25°C; pH = 8 or 9; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Zaher, M. R.; El-Sharief, A. M. Sh.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1982 , vol. 21, # 8 p. 740 - 743
反应条件
sodium hydroxide in 1,4-dioxane
参考文献
Voss,H.
Z. Naturforsch., B: Anorg. Chem., Org. Chem., Biochem., Biophys.,, 1965 , vol. 20, p. 116 - 121
反应条件
triethylamine in 1,4-dioxane
参考文献
Losse,G. et al.
Justus Liebigs Annalen der Chemie, 1965 , vol. 684, p. 236 - 242
反应条件
1: diethyl ether
2: aqueous methanol. NaOH-solution
View Scheme
参考文献
Bergmann; Fruton
Journal of Biological Chemistry, 1942 , vol. 145, p. 247,251
反应条件
1: diethyl ether
2: aqueous methanol. NaOH-solution
View Scheme
参考文献
Bergmann; Fruton
Journal of Biological Chemistry, 1942 , vol. 145, p. 247,251
反应条件
2-Hydroxypyridine; dicyclohexyl-carbodiimide
参考文献
Kapoor; Davis; Graetzer
Journal of pharmaceutical sciences, 1968 , vol. 57, # 9 p. 1514 - 1519
反应条件
1: cross-linked enzyme aggregate of Alcalase / 16 h / 50 °C / Molecular sieve; Enzymatic reaction
2: cross-linked enzyme aggregate of Alcalase; water / 16 h / 37 °C / Enzymatic reaction
View Scheme
参考文献
Nuijens, Timo; Cusan, Claudia; Schepers, Annette C.H.M.; Kruijtzer, John A.W.; Rijkers, Dirk T.S.; Liskamp, Rob M.J.; Quaedflieg, Peter J.L.M.
Journal of Molecular Catalysis B: Enzymatic, 2011 , vol. 71, # 1-2 p. 79 - 84
