2-[[1-(苯基甲氧羰基)吡咯烷-2-羰基]氨基]乙酸合成路线 (共 11 条)
反应条件
hydrogenchloride; sodium hydroxide in acetone Hydrogenation; 2 h;
参考文献
Gudasheva; Vasilevich; Ostrovskaya; Trofimov; Voronina; Skoldinov; Rozantsev
Pharmaceutical Chemistry Journal, 1996 , vol. 30, # 9 p. 562 - 567
反应条件
potassium carbonate in water
参考文献
De Winne, Katleen; Seymour, Leonard W.; Schacht, Etienne H.
European Journal of Pharmaceutical Sciences, 2005 , vol. 24, # 2-3 p. 159 - 168
反应条件
1: 80 percent / ethyl acetate; dimethylformamide / 2 h / -10 - 20 °C 2: 76 percent / NaOH; HCl / acetone / 2 h View Scheme
参考文献
Hashimoto; Tamaki; Sofuku; Muramatsu
Bulletin of the Chemical Society of Japan, 1991 , vol. 64, # 5 p. 1533 - 1541
反应条件
sodium hydrogencarbonate in tetrahydrofuran; water T=0 - 20°C;
参考文献
Chen; Sung; Sung, Kuangsen
Amino Acids, 2010 , vol. 38, # 3 p. 839 - 845
参考文献
Shigenaga; Otagiri; Kanehisa; Okai
Bulletin of the Chemical Society of Japan, 1984 , vol. 57, # 1 p. 103 - 107
反应条件
sodium hydroxide; diethyl ether
参考文献
Abderhalden; Nienburg
Fermentforschung, 1933 , vol. 13, p. 573,594
Full Text Show Details
Migliardi
Arch. Sci. biol., 1941 , vol. 27, p. 327,330
Full Text Show Details
Abderhalden; Merkel
Fermentforschung, 1938 , vol. 15, p. 1,18
反应条件
1: aqueous NaOH 2: pyridine; PCl3 3: aqueous NaOH; dioxane View Scheme
参考文献
Grassmann; Wuensch
Chemische Berichte, 1958 , vol. 91, p. 449,453
反应条件
1: aqueous NaOH 2: pyridine; PCl3 3: aqueous NaOH; dioxane View Scheme
参考文献
Grassmann; Wuensch
Chemische Berichte, 1958 , vol. 91, p. 449,453
反应条件
methanol; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid 1.) anodic oxidation; Pt electrodes, i = 250 mA*cm-2, current equiv.: 16.5 F/mol, 2.) H2O, 25 deg C, 8 h; Yield given. Multistep reaction;
参考文献
Helvetica Chimica Acta, , vol. 72, p. 401 - 425
反应条件
1: palladium; acetic acid; aqueous methanol / Hydrogenation 2: HCl 3: 105 °C / 0 Torr View Scheme
参考文献
Journal of the Chemical Society, , p. 3642,3646