1: bromine; calcium carbonate / chloroform / 0 - 20 °C 2: caesium carbonate; copper(l) iodide; glycine-N',N'-dimethylamide hydrochloride / 1,4-dioxane / 80 °C / |Inert atmosphere View Scheme

calcium chloride in dimethyl sulfoxide T=35°C; 24 h; α-chymotrypsin, McIlvaine buffer, pH 8;

potassium hydroxide isomer of mp: 230 degree;