4-氯-8-甲氧基喹啉-3-甲酸乙酯合成路线 （共 4 条）
反应条件
1: With trichlorophosphate 2 h; Heating / reflux; 2: With ammonia in water
参考文献
Miknis, Greg; Lyssikatos, Joseph P.; Laird, Ellen; Tarlton, Eugene; Buckmelter, Alexandre J.; Ren, Li; Rast, Bryson; Schlacter, Stephen T.; Wenglowsky, Steven Mark
Patent: US2007/49603 A1, 2007 ;
Location in patent: Page/Page column 66 ;
US 20070049603 A1
反应条件
trichlorophosphate T=90°C; 16 h;
参考文献
HIGH POINT PHARMACEUTICALS, LLC; GADDAM, Bapu; POLISETTI, Dharma Rao; GUZEL, Mustafa; VICTORY, Samuel; KOSTURA, Matthew
Patent: WO2011/22216 A1, 2011 ;
Location in patent: Page/Page column 28 ;
WO 2011/022216 A1
反应条件
1: diphenylether / 8 h / 90 °C / Reflux 2: trichlorophosphate / 16 h / 90 °C View Scheme
参考文献
Zask; Gu; Albright; Du; Hogan; Levin; Chen; Killar; Sung; DiJoseph; Sharr; Roth; Skala; Jin; Cowling; Mohler; Barone; Black; March; Skotnicki
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 8 p. 1487 - 1490
反应条件
1: diphenylether / 8 h / 90 °C / Reflux 2: trichlorophosphate / 16 h / 90 °C View Scheme
参考文献
Zask; Gu; Albright; Du; Hogan; Levin; Chen; Killar; Sung; DiJoseph; Sharr; Roth; Skala; Jin; Cowling; Mohler; Barone; Black; March; Skotnicki
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 8 p. 1487 - 1490
