2-羟基-4H-吡啶并[1,2-a]嘧啶-4-酮合成路线

参考文献

AMGEN INC.; BREGMAN, Howard; BUCHANAN, John L.; CHAKKA, Nagasree; DIMAURO, Erin F.; GUNAYDIN, Hakan; GUZMAN PEREZ, Angel; HUA, Zihao; HUANG, Xin
Patent: WO2014/36022 A1, 2014 ;
Location in patent: Paragraph 0224; 0225 ;

886-60-21-苯基-3-(2-吡啶基)-2-硫脲+

1663-67-8丙二酰氯

27420-41-32-羟基-4H-吡啶并[1,2-a]嘧啶-4-酮

参考文献

Deady, Leslie W.; Ganame, Daniel; Hughes, Andrew B.; Quazi, Nurul H.; Zanatta, Shannon D.
Australian Journal of Chemistry, 2002 , vol. 55, # 4 p. 287 - 289

504-29-02-氨基吡啶

27420-41-32-羟基-4H-吡啶并[1,2-a]嘧啶-4-酮

参考文献

AMGEN INC.; BREGMAN, Howard; BUCHANAN, John L.; CHAKKA, Nagasree; DIMAURO, Erin F.; GUNAYDIN, Hakan; GUZMAN PEREZ, Angel; HUA, Zihao; HUANG, Xin
Patent: WO2014/36022 A1, 2014 ;

504-29-02-氨基吡啶+

105-53-3丙二酸二乙酯

59514-86-24-羟基-1,8-萘啶-2(1h)-酮+

27420-41-32-羟基-4H-吡啶并[1,2-a]嘧啶-4-酮

参考文献

Abass, Mohamed; Mayas, Aisha S.
Heteroatom Chemistry, 2007 , vol. 18, # 1 p. 19 - 27

27420-41-32-羟基-4H-吡啶并[1,2-a]嘧啶-4-酮

5654-95-51H-吡咯[2,3-B]吡啶-2,3-二酮

参考文献

Abass, Mohamed; Mayas, Aisha S.
Journal of Chemical Research, 2009 , # 2 p. 93 - 94

27420-41-32-羟基-4H-吡啶并[1,2-a]嘧啶-4-酮

5418-94-02-氯-4H-吡啶并[1,2-a]嘧啶-4-酮

参考文献

Abass, Mohamed; Mayas, Aisha S.
Heteroatom Chemistry, 2007 , vol. 18, # 1 p. 19 - 27